ArticleFrontiers in neurology2020
Ocular Side Effects of Sildenafil That Persist Beyond 24 h-A Case Series.
Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Identification of Emotional Spectrums of Patients Taking an Erectile Dysfunction Medication: Ontology-Based Emotion Analysis of Patient Medication Reviews on Social Media.Journal of medical Internet research · 2023Article
- Retinal toxicity of long term overdose of sildenafil citrate: A case report.American journal of ophthalmology case reports · 2023Article
- Long-term follow-up of retinal morphology and physiology after 2000 mg sildenafil overdose as a means of attempted suicide: a case report.BMC ophthalmology · 2022Article
- The ocular adverse effects of oral drugs.Australian prescriber · 2021Review
- Visual Side Effects Linked to Sildenafil Consumption: An Update.Biomedicines · 2021Review
- Sildenafil-evoked photoreceptor oxidative stress in vivo is unrelated to impaired visual performance in mice.PloS one · 2021Article
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
Acute secondary effects of sildenafil, a first-line pharmacotherapy for erectile dysfunction (ED), include headache, heartburn, skin flush, and vision changes. Generally, these effects subside within 5 h. This is a retrospective report of 17 cases in which patients experienced visual disturbances following 100-mg sildenafil use that persisted for more than 24 h. All 17 patients were healthy men taking sildenafil for the first time without prescriptions who sought consultation at our clinic within 48 h of taking the drug. Diagnostic tests indicated that out of the 17 patients, nine had photophobia, 13 had disrupted color perception, nine had impaired visual acuity, three had deficiencies in stereopsis, six had disrupted contrast sensitivity, and eight had abnormally dilated pupils. These disturbances resolved within 21 days in all 17 cases. There was near-full case overlap between photophobia and color vision impairment. In conclusion, because some individuals have heightened sensitivity to sildenafil, perhaps due to metabolic variance, patients should be started on a modest trial dose.
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