ArticleFrontiers in psychiatry2019
Dynamic Functional Connectivity Strength Within Different Frequency-Band in Schizophrenia.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 34 citations in OpenAlex.
- CCPD under sparsity and low-rank constraints: multi-frequency dynamic functional network connectivity analysis in schizophrenia.Frontiers in neuroscience · 2026Article
- Studying time-resolved functional connectivity via communication theory: on the complementary nature of phase synchronization and sliding window Pearson correlation.bioRxiv : the preprint server for biology · 2025Article
- Abnormal Dynamic Reconstruction of Overlapping Communities in Schizophrenia Patients.Brain sciences · 2024Article
- Prediction of treatment response in major depressive disorder using a hybrid of convolutional recurrent deep neural networks and effective connectivity based on EEG signal.Physical and engineering sciences in medicine · 2024Article
- Enhanced brain structure-function tethering in transmodal cortex revealed by high-frequency eigenmodes.Nature communications · 2023Article
- Altered static and dynamic functional connectivity of habenula in first-episode, drug-naïve schizophrenia patients, and their association with symptoms including hallucination and anxiety.Frontiers in psychiatry · 2023Article
- A schizophrenia study based on multi-frequency dynamic functional connectivity analysis of fMRI.Frontiers in human neuroscience · 2023Article
- Neuroimaging biomarkers for detecting schizophrenia: A resting-state functional MRI-based radiomics analysis.Heliyon · 2022Article
- Abnormal characterization of dynamic functional connectivity in Alzheimer's disease.Neural regeneration research · 2022Article
- Frequency-specific coactivation patterns in resting-state and their alterations in schizophrenia: An fMRI study.Human brain mapping · 2022Article
- Frequency-Specific Analysis of the Dynamic Reconfiguration of the Brain in Patients with Schizophrenia.Brain sciences · 2022Article
- The Clustering Analysis of Time Properties in Patients With Cerebral Small Vessel Disease: A Dynamic Connectivity Study.Frontiers in neurology · 2022Article
- Interhemispheric co-alteration of brain homotopic regions.Brain structure & function · 2021Article
- A unified approach for characterizing static/dynamic connectivity frequency profiles using filter banks.Network neuroscience (Cambridge, Mass.) · 2021Article
- Surface-Based Spontaneous Oscillation in Schizophrenia: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in human neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a complex psychiatric disorder, schizophrenia is interpreted as a "dysconnection" syndrome, which is linked to abnormal integrations in between distal brain regions. Recently, neuroimaging has been widely adopted to investigate how schizophrenia affects brain networks. Furthermore, some studies reported frequency dependence of the abnormalities of functional network in schizophrenia, however, dynamic functional connectivity with frequency dependence is rarely used to explore changes in the whole brain of patients with schizophrenia (SZ). Therefore, in the current study, dynamic functional connectivity strength (dFCS) was performed on resting-state functional magnetic resonance data from 96 SZ patients and 121 healthy controls (HCs) at slow-5 (0.01-0.027 Hz), slow-4 (0.027-0.073 Hz), slow-3 (0.073-0.198 Hz), and slow-2 (0.198-0.25 Hz) frequency bands and further assessed whether the altered dFCS was correlated to clinical symptoms in SZ patients. Results revealed that decreased dFCS of schizophrenia were found in salience, auditory, sensorimotor, visual networks, while increased dFCS in cerebellum, basal ganglia, and prefrontal networks were observed across different frequency bands. Specifically, the thalamus subregion of schizophrenic patients exhibited enhanced dynamic FCS in slow-5 and slow-4, while reduced in slow-3. Moreover, in slow-5 and slow-4, significant interaction effects between frequency and group were observed in the left calcarine cortex, the bilateral inferior orbitofrontal gyrus, and anterior cingulum cortex (ACC). Furthermore, the altered dFCS of insula, thalamus (THA), calcarine cortex, orbitofrontal gyrus, and paracentral lobule were partial correlated with clinical symptoms of SZ patients in slow-5 and slow-4 bands. These results demonstrate the abnormalities of dFCS in schizophrenia patients is rely on different frequency bands and may provide potential implications for exploring the neuropathological mechanism of schizophrenia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.