ArticleFrontiers in physiology2020
Echocardiographic Epicardial Adipose Tissue Thickness for Risk Stratification of Patients With Heart Failure.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Prognostic value of epicardial adipose tissue in heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Efficacy of cardiometabolic drugs in reduction of epicardial adipose tissue: a systematic review and meta-analysis.Cardiovascular diabetology · 2023Pooled it
- Association Between Epicardial Adipose Tissue Thickness and Early Arrhythmia Recurrence After Electrical Cardioversion for Atrial Fibrillation and Atrial Flutter in Patients With and Without Heart Failure-An Observational Study.Medicina (Kaunas, Lithuania) · 2026Observational
- The "Adipo-Muscular" association in heart failure with preserved ejection fraction: synergistic impact of epicardial adipose tissue and skeletal muscle endurance on functional capacity.BMC cardiovascular disorders · 2026Article
- Epicardial adipose tissue as a determinant of heart failure prognosis: insights across ejection fraction phenotypes.Cardiovascular diabetology · 2026Review
- Epicardial fat remodeling in end-stage heart failure with reduced ejection fraction.Cardiovascular diabetology · 2026Article
- Beyond Traditional Risk Factors: Integrating Epicardial Adipose Tissue into the Comorbidity Landscape of HFpEF.Journal of clinical medicine · 2025Review
- Comprehensive assessment of distinct abdominal fat compartments beyond liver content in overweight/obese patients using MRI and ultrasound imaging.Abdominal radiology (New York) · 2025Article
- Serum Lipids, Inflammation, and the Risk of Atrial Fibrillation: Pathophysiological Links and Clinical Evidence.Journal of clinical medicine · 2025Review
- Analysis of the correlation between EAT thickness and prognosis in patients with heart failure with preserved ejection fraction.Frontiers in cardiovascular medicine · 2025Article
- Effects of Heart Failure Therapies on Atrial Fibrillation: Biological and Clinical Perspectives.Antioxidants (Basel, Switzerland) · 2024Review
- Negative association of apelin plasma levels with epicardial fat thickness in patients with stable angina and acute myocardial infarction: A case-control study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
- Longitudinal association of epicardial and thoracic adipose tissues with coronary and cardiac characteristics in psoriasis.Heliyon · 2023Article
- Prognostic value of ventricle epicardial fat volume by cardiovascular magnetic resonance in chronic heart failure.iScience · 2023Article
- Determinants of Arterial Stiffness in Patients with Morbid Obesity. The Role of Echocardiography and Carotid Ultrasound Imaging.Medicina (Kaunas, Lithuania) · 2023Article
- Inflammation and Cardiovascular Diseases in the Elderly: The Role of Epicardial Adipose Tissue.Frontiers in medicine · 2022Review
- Importance of cardiac imaging assessment of epicardial adipose tissue after a first episode of myocardial infarction.Frontiers in cardiovascular medicine · 2022Article
- Epicardial Adipose Tissue and Cardiac Arrhythmias: Focus on Atrial Fibrillation.Frontiers in cardiovascular medicine · 2022Review
- Cardiac Adiposity and Arrhythmias: The Role of Imaging.Diagnostics (Basel, Switzerland) · 2021Review
- Epicardial Adipose Tissue and IL-13 Response to Myocardial Injury Drives Left Ventricular Remodeling After ST Elevation Myocardial Infarction.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsEpicardial adipose tissue (EAT) has been shown to be involved in the pathogenesis and progression of heart failure (HF). In this study we aimed to explore the predictive value of echocardiographic EAT thickness on prognosis of a selected population of HF patients.
methodsThe patient population included n. 69 consecutive patients with systolic HF referred to implantable cardioverter defibrillator (ICD) implantation for primary or secondary prevention. At the time of enrolment, echocardiographic EAT thickness was assessed in all patients along with demographic and clinical data. The study had a median follow-up time of 49.8 months. We assessed the prognostic predictive value of EAT thickness on a composite clinical and arrhythmic outcome including HF related deaths, new hospital admissions for HF worsening, and atrial and life threatening ventricular arrhythmic events. Clinical and arrhythmic outcomes were also evaluated separately.
resultsAt univariate analysis, EAT thickness significantly predicted all the three outcomes considered. Of interest, at multivariate analysis, after adjusting for known risk factor, EAT remained significantly associated to the composite [HR 1.18 (1.09-1.28);
conclusionEchocardiographic assessment of EAT can predict outcome of HF patients and it is significantly associated with both arrhythmic and clinical events. These preliminary findings pave the way for future and larger studies aimed to definitively recognize the prognostic value of this novel risk marker in HF.
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