Evidence map›Paper›PMID 32116693›Full record

ArticleFrontiers in pharmacology2020

Naturally Occurring TPE-CA Maintains Gut Microbiota and Bile Acids Homeostasis

Linlin Liu, Zhenli Liu, Hui Li, Zhiwen Cao, Wen Li, Zhiqian Song, Xiang Li, Aiping Lu, Cheng Lu, Yuanyan Liu

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. mSystems · 2026
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  4. Journal of traditional and complementary medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linlin LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Zhenli LiuInstitution of Basic Theory, China Academy of Chinese Medical Sciences, Beijing, China.
Hui LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Zhiwen CaoSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Wen LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Zhiqian SongInstitution of Basic Theory, China Academy of Chinese Medical Sciences, Beijing, China.
Xiang LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Aiping LuInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Cheng LuInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Yuanyan LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics-induced changes in intestinal flora (dysbiosis) may have various effects on the host. Dysbiosis is associated with numerous metabolites including bile acids, which are produced in the liver from cholesterol and metabolized in the gut by intestinal microbiota. Total phenolic extracts of

Indexed as

antibioticsbile aciddysbiosisintestinal barrier integrityliver–gut axistotal phenolic extracts of Citrus aurantium L.

Identifiers

PMID32116693
PMCPMC7015895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.