Evidence map›Paper›PMID 32116676›Full record

ReviewFrontiers in pharmacology2019

Progress in Genetic Polymorphisms Related to Lipid Disturbances Induced by Atypical Antipsychotic Drugs.

Nana Li, Ting Cao, Xiangxin Wu, Mimi Tang, Daxiong Xiang, Hualin Cai

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
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  8. Associations of theJournal of personalized medicine · 2021
    Article
  9. Review
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  11. Targeting dopamine receptor D2 as a novel therapeutic strategy in endometrial cancer.Journal of experimental & clinical cancer research : CR · 2021
    Article
  12. Article
  13. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nana LiDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, China.
Ting CaoDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, China.
Xiangxin WuDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, China.
Mimi TangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Daxiong XiangDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, China.
Hualin CaiDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic side effects such as weight gain and disturbed lipid metabolism are often observed in the treatment of atypical antipsychotic drugs (AAPDs), which contribute to an excessive prevalence of metabolic syndrome among schizophrenic patients. Great individual differences are observed but the underlying mechanisms are still uncertain. Research on pharmacogenomics indicates that gene polymorphisms involved in the pathways controlling food intake and lipid metabolism may play a significant role. In this review, relevant genes (

Indexed as

5-HT2C receptoratypical antipsychotic drugsleptinmetabolic syndromepharmacogenomicssingle nucleotide polymorphismsweight gain

Identifiers

PMID32116676
PMCPMC7011106
OpenAlexW3004869763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.