Evidence map›Paper›PMID 32116666›Full record

ArticleFrontiers in pharmacology2019

Edible Bird's Nest Protects Against Hyperglycemia-Induced Oxidative Stress and Endothelial Dysfunction.

Dharmani Devi Murugan, Zuhaida Md Zain, Ker Woon Choy, Nor Hisam Zamakshshari, Mel June Choong, Yang Mooi Lim, Mohd Rais Mustafa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dharmani Devi MuruganDepartment of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Zuhaida Md ZainDepartment of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Ker Woon ChoyDepartment of Anatomy, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Malaysia.
Nor Hisam ZamakshshariCentre for Natural Product Research and Drug Discovery (CENAR), Wellness Research Cluster, University of Malaya, Kuala Lumpur, Malaysia.
Mel June ChoongCentre for Cancer Research, Faculty of Medicine and Health Sciences, University Tunku Abdul Rahman, Selangor, Malaysia.
Yang Mooi LimDepartment of Pre-clinical Sciences, Centre for Cancer Research, Faculty of Medicine and Health Sciences, University Tunku Abdul Rahman, Selangor, Malaysia.
Mohd Rais MustafaDepartment of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
University of Malaya · MYUniversiti Tunku Abdul Rahman · MYUniversiti Teknologi MARA · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased oxidative stress by hyperglycemia is a major cause of vascular complications in diabetes. Bird's nest, which is made from the saliva of swiftlets has both medicinal and nutritional values dated back to ancient China. However, its role in improving endothelial dysfunction due to diabetes is yet to be elucidated. The present study examined the protective effect and mechanism of action of the aqueous extract of hydrolyzed edible bird nest (HBN) on endothelium in models of diabetes,

Indexed as

endothelial dysfunctionhydrolyzed bird’s nesthyperglycemianitric oxideoxidative stressreactive oxygen species

Identifiers

PMID32116666
PMCPMC7010601
OpenAlexW3005498983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.