Evidence map›Paper›PMID 32116655›Full record

ArticleFrontiers in aging neuroscience2020

Neuroprotection by the Immunomodulatory Drug Pomalidomide in the

Maria Antonietta Casu, Ignazia Mocci, Raffaella Isola, Augusta Pisanu, Laura Boi, Giovanna Mulas, Nigel H Greig, Maria Dolores Setzu, Anna R Carta

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Article
  11. Article
  12. ACS pharmacology & translational science · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Maria Antonietta CasuCNR Institute of Translational Pharmacology, Cagliari, Italy.
Ignazia MocciCNR Institute of Translational Pharmacology, Cagliari, Italy.
Raffaella IsolaDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Augusta PisanuCNR Institute of Neuroscience, Cagliari, Italy.
Laura BoiDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Giovanna MulasDepartment of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Nigel H GreigNational Institute of Aging (NIA), Drug Design & Development Section, Translational Gerontology Branch, Baltimore, MD, United States.
Maria Dolores SetzuDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Anna R CartaDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
University of Cagliari · ITIstituto di Farmacologia Traslazionale · ITNational Institute on Aging · USNeuroscience Institute · IT

Funding

Pro-inflammatory cytokine lowering anti-inflammatory drugsZIAAG000994 · NIA · NATIONAL INSTITUTE ON AGING · PI GREIG, NIGEL H. · 2016 to 2025
$16.8M
6 · The paper itself

Abstract

The search for new disease-modifying drugs for Parkinson's disease (PD) is a slow and highly expensive process, and the repurposing of drugs already approved for different medical indications is becoming a compelling alternative option for researchers. Genetic variables represent a predisposing factor to the disease and mutations in leucine-rich repeat kinase 2 (LRRK2) locus have been correlated to late-onset autosomal-dominant PD. The common fruit fly

Indexed as

Drosophiladrug repurposingimmunomodulationLRRK2neuroprotectionParkinsonrepositioning

Identifiers

PMID32116655
PMCPMC7031158
OpenAlexW3005589861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.