Evidence map›Paper›PMID 32116654›Full record

ArticleFrontiers in aging neuroscience2020

The Density of Perineuronal Nets Increases With Age in the Inferior Colliculus in the Fischer Brown Norway Rat.

Amir M Mafi, Lindsay N Hofer, Matthew G Russ, Jesse W Young, Jeffrey G Mellott

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amir M MafiDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, United States.
Lindsay N HoferDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, United States.
Matthew G RussDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, United States.
Jesse W YoungDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, United States.
Jeffrey G MellottDepartment of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, OH, United States.
Northeast Ohio Medical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related hearing loss, one of the most frequently diagnosed disabilities in industrialized countries, may result from declining levels of GABA in the aging inferior colliculus (IC). However, the mechanisms of aging and subsequent disruptions of temporal processing in elderly hearing abilities are still being investigated. Perineuronal nets (PNs) are a specialized form of the extracellular matrix and have been linked to GABAergic neurotransmission and to the regulation of structural and synaptic plasticity. We sought to determine whether the density of PNs in the IC changes with age. We combined

Indexed as

agingGABAergicinferior colliculusperineuronal netsWisteria floribunda agglutinin

Identifiers

PMID32116654
PMCPMC7026493
OpenAlexW3005937127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.