Evidence map›Paper›PMID 32116619›Full record

ArticleFrontiers in computational neuroscience2020

Modeling the Effect of Temperature on Membrane Response of Light Stimulation in Optogenetically-Targeted Neurons.

Helton M Peixoto, Rossana M S Cruz, Thiago C Moulin, Richardson N Leão

Open access · goldAbstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Hemodynamic and Electrophysiological Progression of the Rose Bengal Photothrombotic Stroke Model in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Quantitative analysis of the optogenetic excitability of CA1 neurons.Frontiers in computational neuroscience · 2023
    Article
  9. Article
  10. Article
  11. Optical control of purinergic signaling.Purinergic signalling · 2021
    Review
  12. Wireless, battery-free, subdermally implantable platforms for transcranial and long-range optogenetics in freely moving animals.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Helton M PeixotoSchool of Science and Technology (ECT), Federal University of Rio Grande do Norte (UFRN), Natal, Brazil.
Rossana M S CruzElectrical Engineering Department, Federal Institute of Paraiba (IFPB), Joao Pessoa, Brazil.
Thiago C MoulinInstitute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Richardson N LeãoNeurodynamics Lab, Brain Institute, Federal University of Rio Grande do Norte, Natal, Brazil.
Universidade Federal do Rio Grande do Norte · BRInstituto Federal de Educação, Ciência e Tecnologia do Pará · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optogenetics is revolutionizing Neuroscience, but an often neglected effect of light stimulation of the brain is the generation of heat. In extreme cases, light-generated heat kills neurons, but mild temperature changes alter neuronal function. To date, most

Indexed as

bio-heatfinite element methodHodgkin-Huxley modeloptogeneticstemperature

Identifiers

PMID32116619
PMCPMC7010719
OpenAlexW2940787717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.