ArticleFrontiers in integrative neuroscience2019
Biomarker Acquisition and Quality Control for Multi-Site Studies: The Autism Biomarkers Consortium for Clinical Trials.
Article in Frontiers in integrative neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of very early interventions on neurodevelopmental outcomes for infants and toddlers at increased likelihood of or diagnosed with autism: A systematic review and meta-analysis.Autism research : official journal of the International Society for Autism Research · 2023Pooled it
- Cortical Network Overconnectivity Relates to Sensory, Cognitive, and Social Dimensions in Young Children With Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2026Article
- Reduced social prioritization: An underlying mechanism driving slower latency to look at faces in autism.Journal of psychopathology and clinical science · 2026Article
- Multilevel Multivariate Functional Principal Component Analysis of Evoked and Induced Event-Related Spectral Perturbations.Statistics in biosciences · 2025Article
- Face perception, attention, and memory as predictors of social change in autistic children.Journal of neurodevelopmental disorders · 2025Observational
- Use of computer vision analysis for labeling inattention periods in EEG recordings with visual stimuli.Scientific reports · 2025Article
- The GREENBEAN checklist for reporting studies evaluating the effectiveness of EEG-based biomarkers.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Review
- Visual Attention in Joint Attention Bids: A Comparison Between Toddlers with Autism Spectrum Disorder and Typically Developing Toddlers.Journal of autism and developmental disorders · 2025Article
- Constrained Multivariate Functional Principal Components Analysis for Novel Outcomes in Eye-Tracking Experiments.Statistics in biosciences · 2024Article
- Linguistic summarization of visual attention and developmental functioning of young children with autism spectrum disorder.Health information science and systems · 2024Article
- Multi-modal EEG NEO-FFI with Trained Attention Layer (MENTAL) for mental disorder prediction.Brain informatics · 2024Article
- Parsing evoked and induced gamma response differences in Autism: A visual evoked potential study.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Modeling intra-individual inter-trial EEG response variability in autism.Statistics in medicine · 2024Article
- EEG Biomarkers for Autism: Rational, Support, and the Qualification Process.Advances in neurobiology · 2024Review
- Biomarker Methodologies: A NIMH Perspective.Advances in neurobiology · 2024Review
- The Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC-CT) feasibility study.Autism research : official journal of the International Society for Autism Research · 2023Article
- Attention Allocation During Exploration of Visual Arrays in ASD: Results from the ABC-CT Feasibility Study.Journal of autism and developmental disorders · 2023Article
- Electroencephalographic (EEG) Biomarkers in Genetic Neurodevelopmental Disorders.Journal of child neurology · 2023Review
- Tubers Affecting the Fusiform Face Area Are Associated with Autism Diagnosis.Annals of neurology · 2023Article
- The Autism Biomarkers Consortium for Clinical Trials: Initial Evaluation of a Battery of Candidate EEG Biomarkers.The American journal of psychiatry · 2023Article
Corrections and comments
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Authors and funding
22 authors.
Funding
Abstract
The objective of the Autism Biomarkers Consortium for Clinical Trials (ABC-CT) is to evaluate a set of lab-based behavioral video tracking (VT), electroencephalography (EEG), and eye tracking (ET) measures for use in clinical trials with children with autism spectrum disorder (ASD). Within the larger organizational structure of the ABC-CT, the Data Acquisition and Analytic Core (DAAC) oversees the standardization of VT, EEG, and ET data acquisition, data processing, and data analysis. This includes designing and documenting data acquisition and analytic protocols and manuals; facilitating site training in acquisition; data acquisition quality control (QC); derivation and validation of dependent variables (DVs); and analytic deliverables including preparation of data for submission to the National Database for Autism Research (NDAR). To oversee consistent application of scientific standards and methodological rigor for data acquisition, processing, and analytics, we developed standard operating procedures that reflect the logistical needs of multi-site research, and the need for well-articulated, transparent processes that can be implemented in future clinical trials. This report details the methodology of the ABC-CT related to acquisition and QC in our Feasibility and Main Study phases. Based on our acquisition metrics from a preplanned interim analysis, we report high levels of acquisition success utilizing VT, EEG, and ET experiments in a relatively large sample of children with ASD and typical development (TD), with data acquired across multiple sites and use of a manualized training and acquisition protocol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.