Evidence map›Paper›PMID 32116559›Full record

ArticleFrontiers in cellular neuroscience2020

TTX-Resistant Sodium Channels Functionally Separate Silent From Polymodal C-nociceptors.

Robin Jonas, Vincenzo Prato, Stefan G Lechner, Gerbrand Groen, Otilia Obreja, Fiona Werland, Roman Rukwied, Andreas Klusch, Marlen Petersen, Richard W Carr and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Robin JonasDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Vincenzo PratoInstitute of Pharmacology, University of Heidelberg, Heidelberg, Germany.
Stefan G LechnerInstitute of Pharmacology, University of Heidelberg, Heidelberg, Germany.
Gerbrand GroenDepartment of Anesthesiology, Groningen University, Groningen, Netherlands.
Otilia ObrejaDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Fiona WerlandDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Roman RukwiedDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Andreas KluschDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Marlen PetersenDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Richard W CarrDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Martin SchmelzDepartment of Experimental Pain Research, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pronounced activity-dependent slowing of conduction has been used to characterize mechano-insensitive, "silent" nociceptors and might be due to high expression of Na

Indexed as

action potential conductionactivity-dependent slowing of conductionaxonal calcium imagingnociceptor classestetrodotoxin

Identifiers

PMID32116559
PMCPMC7018684
OpenAlexW3005061164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.