Evidence map›Paper›PMID 32116489›Full record

ArticleFrontiers in neuroscience2020

Preliminary Evidence That CD38 Moderates the Association of Neuroticism on Amygdala-Subgenual Cingulate Connectivity.

Benjamin A Tabak, Katherine S Young, Jared B Torre, Baldwin M Way, Lisa J Burklund, Naomi I Eisenberger, Matthew D Lieberman, Michelle G Craske

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. CD38 connects the heart and brain.Translational psychiatry · 2025
    Review
  4. Review
  5. Article
  6. Observational
  7. Oxytocin Pathway Gene (Frontiers in psychiatry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Benjamin A TabakDepartment of Psychology, Southern Methodist University, Dallas, TX, United States.
Katherine S YoungSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Jared B TorreDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
Baldwin M WayDepartment of Psychology, The Ohio State University, Columbus, OH, United States.
Lisa J BurklundDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
Naomi I EisenbergerDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
Matthew D LiebermanDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
Michelle G CraskeDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
University of California, Los Angeles · USKing's College London · GBSouthern Methodist University · USThe Ohio State University · US

Funding

PREVENTION RESEARCH TRAINING:URBAN CHILDREN'S MENT HLTHT32MH015750 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHRISTINE DUNKEL SCHETTER · 1985 to 2026
$6.2M
Neural mediators of behavior therapy for anxietyR21MH081299 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CRASKE, MICHELLE G · 2008 to 2009
$402k
NIMH NIH HHS R21 MH081299NIMH NIH HHS T32 MH015750
6 · The paper itself

Abstract

CD38 genetic variation has been associated with autism spectrum disorders and social anxiety disorder, which may result from CD38's regulation of oxytocin secretion. Converging evidence has found that the rs3796863 A-allele contributes to increased social sensitivity compared to the CC genotype. The current study examined the moderating role of CD38 genetic variants (rs3796863 and rs6449182) that have been associated with enhanced (or reduced) social sensitivity on neural activation related to neuroticism, which is commonly elevated in individuals with social anxiety and depression. Adults (

Indexed as

CD38fMRIfunctional connectivityneuroticismoxytocinpsychopathology

Identifiers

PMID32116489
PMCPMC7033443
OpenAlexW3006078540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.