Evidence map›Paper›PMID 32116474›Full record

SynthesisJournal of interventional cardiology2020

Hydration Strategies for Preventing Contrast-Induced Acute Kidney Injury: A Systematic Review and Bayesian Network Meta-Analysis.

Qiuping Cai, Ran Jing, Wanfen Zhang, Yushang Tang, Xiaoping Li, Tongqiang Liu

Abstract readNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. ISCCM Guidelines on Acute Kidney Injury and Renal Replacement Therapy.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  8. Renal outcomes of suprarenalCardiovascular diagnosis and therapy · 2022
    Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiuping CaiDivision of Nephrology, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou 213003, Jiangsu, China.
Ran JingDivision of Nephrology, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou 213003, Jiangsu, China.
Wanfen ZhangDivision of Nephrology, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou 213003, Jiangsu, China.
Yushang TangDivision of Nephrology, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou 213003, Jiangsu, China.
Xiaoping LiDivision of Nephrology, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou 213003, Jiangsu, China.
Tongqiang LiuDivision of Nephrology, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou 213003, Jiangsu, China.ORCID https://orcid.org/0000-0002-5990-7251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMany previous studies have examined the effect of different hydration strategies on prevention of contrast-induced acute kidney injury (CI-AKI), but the optimal strategy is unknown. We performed a network meta-analysis (NWM) of these previous studies to identify the optimal strategy. METHODS AND

resultsWeb of Science, PubMed, OVID Medline, and Cochrane Library were searched from their inception dates to September 30, 2018. Randomized controlled trials (RCTs) were selected based on strict inclusion criteria, and a Bayesian NWM was performed using WinBUGS V.1.4.3. We finally analyzed 60 eligible RCTs, which examined 21,293 patients and 2232 CI-AKI events. Compared to intravenous 0.9% sodium chloride (reference), intravenous sodium bicarbonate (OR [95% CI]: 0.74 [0.57, 0.93]), hemodynamic guided hydration (0.41 [0.18, 0.93]), and RenalGuard guided hydration (0.32 [0.14, 0.70]) significantly reduced the occurrence of CI-AKI. Oral hydration and intravenous 0.9% sodium chloride were each noninferior to no hydration in preventing CI-AKI. Intravenous 0.9% sodium chloride, sodium bicarbonate, and hemodynamic guided hydration were each noninferior to oral hydration in preventing CI-AKI. Based on surface under the cumulative ranking curve values, the RenalGuard system was best (0.974) and hemodynamic guided hydration was second best (0.849).

conclusionThere was substantial evidence to support the use of RenalGuard or hemodynamic guided hydration for preventing CI-AKI in high-risk patients, especially those with chronic kidney disease or cardiac dysfunction.

Indexed as

Acute Kidney InjuryContrast MediaFluid TherapyHumansRisk AdjustmentContrast Media

Identifiers

PMID32116474
PMCPMC7036123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.