ArticleAmerican journal of physiology. Renal physiology2020
Gene knockout of the Na
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Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Glucagon receptor agonist aggravates a murine model of Balkan nephropathy.American journal of physiology. Renal physiology · 2026Article
- Renal glucose metabolic enzyme expression during AKI-to-CKD transition.International urology and nephrology · 2026Article
- Glomerular hyperfiltration and enhanced sensitivity to kidney ischemia reperfusion with a blunted KIM-1 response in young male aging-accelerated SAMP8 mice.American journal of physiology. Renal physiology · 2026Article
- ASK1 limits kidney glucose reabsorption, growth, and mid-late proximal tubule KIM-1 induction when diabetes and Western diet are combined with SGLT2 inhibition.American journal of physiology. Renal physiology · 2025Article
- SGLT2 inhibition mitigates transition from acute kidney injury to chronic kidney disease by suppressing ferroptosis.Scientific reports · 2024Article
- SGLT2 inhibition promotes glomerular repopulation by cells of renin lineage in experimental kidney disease.Acta physiologica (Oxford, England) · 2024Article
- SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy.American journal of physiology. Renal physiology · 2024Article
- Deletion, but Not Heterozygosity, of eNOS Raises Blood Pressure and Aggravates Nephropathy in BTBR ob/ob Mice.Nephron · 2024Article
- Knockdown of TMEM30A in renal tubular epithelial cells leads to reduced glucose absorption.BMC nephrology · 2023Article
- Renal Oxygen Demand and Nephron Function: Is Glucose a Friend or Foe?International journal of molecular sciences · 2023Review
- Dapagliflozin alleviates renal fibrosis in a mouse model of adenine-induced renal injury by inhibiting TGF-β1/MAPK mediated mitochondrial damage.Frontiers in pharmacology · 2023Article
- Review
- Empagliflozin Enhances Autophagy, Mitochondrial Biogenesis, and Antioxidant Defense and Ameliorates Renal Ischemia/Reperfusion in Nondiabetic Rats.Oxidative medicine and cellular longevity · 2022Article
- Sodium-Glucose Cotransporter-2 Inhibitors in Vascular Biology: Cellular and Molecular Mechanisms.Cardiovascular drugs and therapy · 2021Review
- Effects of SGLT2 Inhibitors beyond Glycemic Control-Focus on Myocardial SGLT1.International journal of molecular sciences · 2021Review
- Review
- The Sodium-Glucose Cotransporter-2 Inhibitor Canagliflozin Alleviates Endothelial Dysfunction FollowingInternational journal of molecular sciences · 2021Article
- Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice.Clinical science (London, England : 1979) · 2021Article
- Effects of SGLT2 Inhibitors on Kidney and Cardiovascular Function.Annual review of physiology · 2021Review
- Glucose Metabolism in Acute Kidney Injury and Kidney Repair.Frontiers in medicine · 2021Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Josselin NespouxDepartment of Medicine, University of California, and Veterans Affairs San Diego Healthcare System , San Diego, California.
Rohit PatelDepartment of Medicine, University of California, and Veterans Affairs San Diego Healthcare System , San Diego, California.
Haiyan ZhangDepartment of Pathology, University of California, San Diego, California.
Winnie HuangDepartment of Medicine, University of California, and Veterans Affairs San Diego Healthcare System , San Diego, California.
Brent FreemanDepartment of Medicine, University of California, and Veterans Affairs San Diego Healthcare System , San Diego, California.
Paul W SandersDepartments of Medicine, Cell, and Developmental and Integrative Biology, University of Alabama at Birmingham, and Department of Veterans Affairs Medical Center, Birmingham, Alabama.
Young Chul KimDepartment of Medicine, University of California, and Veterans Affairs San Diego Healthcare System , San Diego, California.
Volker VallonDepartment of Medicine, University of California, and Veterans Affairs San Diego Healthcare System , San Diego, California.
VA San Diego Healthcare System · USUniversity of Alabama at Birmingham · USUniversity of California, San Diego · US
Funding
UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3MGlomerular and Tubular Function in the Diabetic KidneyR01DK112042 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI SCOTT Culver THOMSON, Volker Vallon · 2017 to 2026
$4.1MThe Contribution of Kidney Disease to Age-Associated Cognitive DeclineRF1AG061296 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MAHER, PAMELA ANNE · 2019 to 2019
$3.2MRole of tubuloglomerular feedback in the development of hypertension in diabetesR01HL142814 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2019 to 2022
$2.4MUnraveling Kidney Physiology, Pathophysiology & Therapeutics: A Modeling ApproachR01DK106102 · NIDDK · DUKE UNIVERSITY · PI LAYTON, ANITA · 2016 to 2019
$1.4MNHLBI NIH HHS R01 HL142814NIA NIH HHS RF1 AG061296NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK106102NIDDK NIH HHS R01 DK112042
Abstract
In the early proximal tubule, Na
Indexed as
Acute Kidney InjuryAnimalsBiomarkersBlood GlucoseDisease Models, AnimalGlomerular Filtration RateKidneyMice, Inbred C57BLMice, KnockoutRenal EliminationRenal ReabsorptionReperfusion InjurySodium-Glucose Transporter 2Time FactorsBiomarkersBlood GlucoseSlc5a2 protein, mouseSodium-Glucose Transporter 2acute kidney injuryNa+-glucose cotransporter 2sodium-glucose cotransport
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What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.