ArticleHuman brain mapping2020
Functional magnetic resonance imaging (fMRI) item analysis of empathy and theory of mind.
Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
45 citing papers in PubMed.
- Cognitive Reappraisal and Expressive Suppression Evoke Distinct Neural Connections during Interpersonal Emotion Regulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Trial
- Boosting Empathy and Compassion Through Mindfulness-Based and Socioemotional Dyadic Practice: Randomized Controlled Trial With App-Delivered Trainings.Journal of medical Internet research · 2023Trial
- Neural mechanism underlying the beneficial effect of Theory of Mind psychotherapy on early-onset schizophrenia: a randomized controlled trial.Journal of psychiatry & neuroscience : JPNTrial
- Childhood maltreatment impacts the activity of the neural empathy but not theory of mind network: findings from a transdiagnostic sample.European archives of psychiatry and clinical neuroscience · 2026Article
- Disrupted brain functional networks in adolescents and young adults with gaming disorder during social interaction: An fNIRS study.Psychological medicine · 2026Article
- The neurocognitive aspects of empathy and theory of mind in pragmatic language processing.Cognitive, affective & behavioral neuroscience · 2026Article
- Theory of mind difficulties in people with social anhedonia: Evidence from behavioural and task-based functional magnetic resonance imaging findings.Schizophrenia research. Cognition · 2026Article
- Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology.Annals of neurology · 2026Review
- "Take the Rough With the Smooth": Modesty Modulates Neurocognitive and Emotional Processing of Social Feedback.Human brain mapping · 2025Article
- Securely stressed: association between attachment and empathic stress in romantic couples.Scientific reports · 2025Article
- Unveiling the Role of Theory of Mind: Neural Response to Emotional Stimuli in Context.Affective science · 2025Article
- Adult age differences in the integration of values for self and other.Scientific reports · 2025Article
- Validity and reliability study of the Turkish version of the Empathy Quotient- 8 in Turkish university students.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2025Article
- Validation of the Cognitive-Emotional Perspective Taking test in patients with neurodegeneration.Journal of Alzheimer's disease : JAD · 2025Article
- Speaker differences in volitional voice modulation reflected in empathy and functional activation patterns.PloS one · 2025Article
- Early Neural Development of Social Interaction Perception: Evidence from Voxel-Wise Encoding in Young Children and Adults.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Spontaneous brain activity associated with individual differences in decisional and emotional forgiveness.Brain imaging and behavior · 2024Article
- Multidimensional neural representations of social features during movie viewing.Social cognitive and affective neuroscience · 2024Article
- Risk factors for internalizing symptoms: The influence of empathy, theory of mind, and negative thinking processes.Human brain mapping · 2024Article
- The semantics of gaze in person perception: a novel qualitative-quantitative approach.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
In contrast to conventional functional magnetic resonance imaging (fMRI) analysis across participants, item analysis allows generalizing the observed neural response patterns from a specific stimulus set to the entire population of stimuli. In the present study, we perform an item analysis on an fMRI paradigm (EmpaToM) that measures the neural correlates of empathy and Theory of Mind (ToM). The task includes a large stimulus set (240 emotional vs. neutral videos to probe empathic responding and 240 ToM or factual reasoning questions to probe ToM), which we tested in two large participant samples (N = 178, N = 130). Both, the empathy-related network comprising anterior insula, anterior cingulate/dorsomedial prefrontal cortex, inferior frontal gyrus, and dorsal temporoparietal junction/supramarginal gyrus (TPJ) and the ToM related network including ventral TPJ, superior temporal gyrus, temporal poles, and anterior and posterior midline regions, were observed across participants and items. Regression analyses confirmed that these activations are predicted by the empathy or ToM condition of the stimuli, but not by low-level features such as video length, number of words, syllables or syntactic complexity. The item analysis also allowed for the selection of the most effective items to create optimized stimulus sets that provide the most stable and reproducible results. Finally, reproducibility was shown in the replication of all analyses in the second participant sample. The data demonstrate (a) the generalizability of empathy and ToM related neural activity and (b) the reproducibility of the EmpaToM task and its applicability in intervention and clinical imaging studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.