Evidence map›Paper›PMID 32115429›Full record

ArticleThe Journal of rheumatology2020

Psychological and Pain Sensitization Characteristics Are Associated With Patellofemoral Osteoarthritis Symptoms: The Multicenter Osteoarthritis Study.

Natalie J Collins, Tuhina Neogi, Bill Vicenzino, Ali Guermazi, Frank W Roemer, Cora E Lewis, James C Torner, Michael C Nevitt, Joshua J Stefanik

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The Journal of rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Natalie J CollinsN. Collins, PT, PhD, B. Vicenzino, PT, PhD, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia; n.collins1@uq.edu.au.ORCID 0000-0001-9950-0192
Tuhina NeogiT. Neogi, MD, PhD, A. Guermazi, MD, PhD, School of Medicine, Boston University, Boston Massachusetts, USA.ORCID 0000-0002-9515-1711
Bill VicenzinoN. Collins, PT, PhD, B. Vicenzino, PT, PhD, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.ORCID 0000-0003-0253-5933
Ali GuermaziT. Neogi, MD, PhD, A. Guermazi, MD, PhD, School of Medicine, Boston University, Boston Massachusetts, USA.ORCID 0000-0002-9374-8266
Frank W RoemerF.W. Roemer, MD, Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany.ORCID 0000-0001-9238-7350
Cora E LewisC.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
James C TornerJ.C. Torner, PhD, Department of Epidemiology, The University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-0979-4874
Michael C NevittM.C. Nevitt, MPH, PhD, Department of Epidemiology and Biostatistics, University of California San Francisco, California, USA.
Joshua J StefanikJ.J. Stefanik, PT, PhD, Department of Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0002-9250-2061
Boston University · USQueensland University of Technology · AUFriedrich-Alexander-Universität Erlangen-Nürnberg · DENortheastern University · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of Iowa · US

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Susan Poland Giancola · 2013 to 2026
$60.5M
Multicenter Osteoarthritis Study (MOST) Second RenewalU01AG019069 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEVITT, MICHAEL C · 2001 to 2020
$21.7M
WORK DISABILITY-- PERSONS WITH RHEUMATOID ARTHRITISP60AR047785 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2016
$18.0M
Multicenter Osteoarthritis Study (MOST) Second Renewal: Iowa Clinical CenterU01AG018832 · NIA · UNIVERSITY OF IOWA · PI SEGAL, NEIL A, TORNER, JAMES C · 2001 to 2020
$14.1M
Multicenter Osteoarthritis Study (MOST) Second Renewal - Boston UniversityU01AG018820 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2019
$13.6M
Multicenter Osteoarthritis Study (MOST) Second Renewal - UAB Clinical CenterU01AG018947 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 2001 to 2020
$13.2M
Research and Evaluation Support Core Unit (RESCU Core)P30AR072571 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Michael Paul Lavalley · 2019 to 2026
$6.9M
Central Sensitization in Post-Knee Replacement Pain and Relation to OA PathologyR01AR062506 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NEOGI, TUHINA · 2012 to 2016
$2.4M
The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and PainK24AR070892 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI TUHINA NEOGI · 2017 to 2026
$1.1M
The Relation of Altered Pain Processing to Impact Loading and Response to a Gait Retraining Treatment in Knee OsteoarthritisK23AR070913 · NIAMS · UNIVERSITY OF DELAWARE · PI STEFANIK, JOSHUA JON · 2017 to 2021
$828k
NIAMS NIH HHS K23 AR070913NIAMS NIH HHS K24 AR070892NIAMS NIH HHS P30 AR072571NIAMS NIH HHS P60 AR047785NIAMS NIH HHS R01 AR062506NIA NIH HHS U01 AG018820NIA NIH HHS U01 AG018832NIA NIH HHS U01 AG018947NIA NIH HHS U01 AG019069NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

objectiveDetermine the relation of symptomatic and structural features of patellofemoral osteoarthritis (PFOA) to psychological characteristics and measures of pain sensitization, in older adults with or at risk of knee osteoarthritis (OA).

methodsThis study included 1112 participants from the Multicenter Osteoarthritis Study (713 females, mean age 66.8 ± SD 7.6 yrs, body mass index 29.5 ± 4.8 kg/m

resultsCompared with no PFOA, those with PF symptoms with or without MRI PFOA had significantly greater odds of depressive symptoms, catastrophizing, and patellar TS (OR range 1.5-2.01), and those with PF symptoms without MRI PFOA had significantly greater odds of wrist TS (OR 1.66). Males with PF symptoms without MRI PFOA had significantly lower pressure PPT at the patella compared with no PFOA and those with MRI PFOA only (no symptoms). There were no significant differences at the wrist for males, or the patella or wrist for females.

conclusionPersons with PFOA symptoms, regardless of MRI PFOA status, are more likely to demonstrate depressive symptoms, catastrophizing, and TS. Males with PFOA symptoms without MRI PFOA demonstrate local hyperalgesia.

Indexed as

Osteoarthritis, KneePatellofemoral JointAgedFemaleHumansKnee JointMagnetic Resonance ImagingMalePainkneemagnetic resonance imagingosteoarthritispain

Identifiers

PMID32115429
PMCPMC8005266
OpenAlexW3008334816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.