Evidence map›Paper›PMID 32115369›Full record

ArticleCurrent problems in pediatric and adolescent health care2020

Doc, can you test me for "toxic metals"? Challenges of testing for toxicants in patients with environmental concerns.

Lauren Zajac, Sarah A Johnson, Marissa Hauptman

Open access · greenAbstract readCase Reports
In one paragraph

Article in Current problems in pediatric and adolescent health care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Lauren ZajacDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1057, New York, NY 10029, United States; Region 2 Pediatric Environmental Health Specialty Unit (PEHSU), Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: lauren.zajac@mssm.edu.
Sarah A JohnsonDepartment of Managed Care, Island Peer Review Organization (IPRO), New Hyde Park, NY, United States.
Marissa HauptmanRegion 1 Pediatric Environmental Health Specialty Unit (PEHSU), Boston Children's Hospital, Boston, MA, United States; Pediatric Environmental Health Center, Division of General Pediatrics, Boston Children's Hospital, Boston, MA, United States; Department of Pediatrics, Harvard Medical School, Boston, MA, United States.
Boston Children's Hospital · USIcahn School of Medicine at Mount Sinai · USIsland Peer Review Organization · US

Funding

The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
MEETING THE ENVIRONMENTAL HEALTH NEEDS OF CHILDRENU61TS000237 · TS · AMERICAN ACADEMY OF PEDIATRICS · PI SACHDEVA, RAMESH · 2014 to 2015
$2.2M
ATSDR CDC HHS U61 TS000237NIEHS NIH HHS P30 ES023515
6 · The paper itself

Abstract

Laboratory testing is an important tool to assist clinicians in evaluation of patients with potential environmentally-related illness, however, it can be challenging to select or interpret the appropriate toxicological tests. Recent advances in analytical techniques and expanded consumer access to environmental laboratories led to a rise in laboratory testing for various environmental toxicants, including metals. However, most environmental tests have scant clinical evidence and are not validated for clinical use. While the tests themselves may not present direct harm to the patients, the results of inappropriately selected tests may lead to significant patient stress and unnecessary follow-up or treatment. Given the lack of environmental health content in medical training, pediatricians may feel ill-equipped to address most environmental issues they encounter in practice, including the interpretation of environmental toxicant lab results. This article provides an overview of how to approach a child and family with environmental health concerns about "toxic metals", select appropriate metal tests if indicated, and enlist the assistance of the Pediatric Environmental Health Specialty Units (PEHSU) for further management guidance.

Indexed as

ChildEnvironmental ExposureFatigueFemaleHeavy Metal PoisoningHumansLaboratories

Identifiers

PMID32115369
PMCPMC7230008
OpenAlexW3007409287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.