Evidence map›Paper›PMID 32115311›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2020

Aggression Prevention Training for Individuals With Dementia and Their Caregivers: A Randomized Controlled Trial.

Mark E Kunik, Melinda A Stanley, Srijana Shrestha, David Ramsey, Sheila Richey, Lynn Snow, Jessica Freshour, Tracy Evans, Michael Newmark, Susan Williams and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Validation of a Brief Screen to Identify Persons With Dementia at Risk for Behavioral Problems.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2021
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mark E KunikHouston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety (MEK, DR, TE, ABA), Houston, TX; VA South Central Mental Illness Research, Education and Clinical Center (a virtual center) (MEK, DR, TE, ABA); Baylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX; Michael E. DeBakey VA Medical Center (MEK, SR, JF), Houston, TX. Electronic address: mkunik@bcm.edu.
Melinda A StanleyBaylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX.
Srijana ShresthaBaylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX; Wheaton College (SS), Norton, MA.
David RamseyHouston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety (MEK, DR, TE, ABA), Houston, TX; VA South Central Mental Illness Research, Education and Clinical Center (a virtual center) (MEK, DR, TE, ABA); Baylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX.
Sheila RicheyBaylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX; Michael E. DeBakey VA Medical Center (MEK, SR, JF), Houston, TX.
Lynn SnowTuscaloosa VA Medical Center (LS), Tuscaloosa, AL; The University of Alabama Center for Mental Health and Aging (LS), Tuscaloosa, AL.
Jessica FreshourMichael E. DeBakey VA Medical Center (MEK, SR, JF), Houston, TX.
Tracy EvansHouston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety (MEK, DR, TE, ABA), Houston, TX; VA South Central Mental Illness Research, Education and Clinical Center (a virtual center) (MEK, DR, TE, ABA); Baylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX.
Michael NewmarkBaylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX; Kelsey Seybold Research Foundation (MN), West University Place, TX.
Susan WilliamsBaylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX.
Nancy WilsonBaylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX.
Amber B AmspokerHouston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety (MEK, DR, TE, ABA), Houston, TX; VA South Central Mental Illness Research, Education and Clinical Center (a virtual center) (MEK, DR, TE, ABA); Baylor College of Medicine (MEK, MAS, SS, DR, SR, TE, MN, SW, NW, ABA), Houston, TX.

Funding

Aggression Prevention Training for Caregivers of Persons with DementiaR01NR014657 · NINR · BAYLOR COLLEGE OF MEDICINE · PI KUNIK, MARK E. · 2014 to 2018
$2.8M
NINR NIH HHS R01 NR014657
6 · The paper itself

Abstract

objectiveInternational appeals call for interventions to prevent aggression and other behavioral problems in individuals with dementia (IWD). Aggression Prevention Training (APT), based on intervening in three contributors to development of aggression (IWD pain, IWD depression, and caregiver-IWD relationship problems) aims to reduce incidence of aggression in IWD over 1 year.

designRandomized, controlled trial.

settingThree clinics that assess, diagnose, and treat dementia.

participantsTwo hundred twenty-eight caregiver-IWD dyads who screened positive for IWD pain, IWD depression, or caregiver-IWD relationship problems randomized to APT or Enhanced Usual Primary Care (EU-PC).

interventionAPT, a skills-based intervention delivered over 3 months to address pain/depression/caregiver-IWD relationship issues. EU-PC included printed material on dementia and community resources; and eight brief, weekly support calls. MEASUREMENTS: The primary outcome was incidence of aggression over 1 year, determined by the Cohen Mansfield Agitation Inventory-Aggression Subscale. Secondary outcomes included pain, depression, caregiver-IWD relationship, caregiver burden, positive caregiving, behavior problems, and anxiety.

resultsAggression incidence and secondary outcomes did not differ between groups. However, in those screening positive for IWD depression or caregiver-IWD relationship problems, those receiving EU-PC had significant increases in depression and significant decreases in quality of the caregiver-IWD relationship, whereas those receiving APT showed no changes in these outcomes over time.

conclusionThe cost to patients, family, and society of behavioral problems in IWD, along with modest efficacy of most pharmacologic and nonpharmacologic interventions, calls for more study of novel preventive approaches.

Indexed as

Adaptation, PsychologicalAgedAged, 80 and overAggressionCaregiversDementiaDepressionFemaleHumansIncidenceMalePainProportional Hazards ModelsPsychiatric Status Rating ScalesTexasAggressioncaregiverdementiadepressionpainrandomized controlled trial

Identifiers

PMID32115311
PMCPMC7246139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.