Evidence map›Paper›PMID 32115023›Full record

ArticlePoultry science2020

Research Note: Correlation analysis of interleukin-6, interleukin-8, and C-C motif chemokine ligand 2 gene expression in chicken spleen and cecal tissues after Eimeria tenella infection in vivo.

Hailiang Yu, Wenbin Zou, Xiaohui Wang, Guojun Dai, Tao Zhang, Genxi Zhang, Kaizhou Xie, Jinyu Wang, Huiqiang Shi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Comprehensive analysis of gut microbiome and host transcriptome in chickens afterFrontiers in cellular and infection microbiology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Coccidia-Microbiota Interactions and Their Effects on the Host.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hailiang YuKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Wenbin ZouKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Xiaohui WangKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Guojun DaiKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China. Electronic address: daigj@yzu.edu.cn.
Tao ZhangKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Genxi ZhangKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Kaizhou XieKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Jinyu WangKey Laboratory of Animal Genetics, Breeding and Reproduction and Molecular Design of Jangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Huiqiang ShiJiangsu Jinghai Poultry Group Co., Ltd., Haimen 226100, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IL-6, IL-8, and C-C motif chemokine ligand 2 (CCLi2) are important factors in inflammatory and immune responses. To investigate their relationships in the spleen and cecum and between coccidiosis-infected and uninfected states, we performed quantitative real-time PCR to compare the relative expression difference of IL-6, IL-8, and CCLi2 in the same tissues between the infection and control groups. In addition, the correlations of the relative expression levels of these 3 genes were determined in the same and different tissues within the same group. The results showed that the expression levels of IL-6, IL-8, and CCLi2 in the spleen and cecum of the infected group were all higher than those of the uninfected group (P < 0.05). The correlation coefficients among the IL-6, IL-8, and CCLi2 expression levels in the spleen or cecum were all positive in both the infection and control groups. In the spleen tissues, CCLi2 expression was strongly correlated with IL-6 and IL-8 in the uninfected group (P < 0.01), and the correlation coefficients reached 0.853 (R

Indexed as

Gene ExpressionAnimalsAvian ProteinsCecumChemokine CCL2CoccidiosisEimeria tenellaInterleukin-6Interleukin-8LigandsPoultry DiseasesSpleenAvian ProteinsChemokine CCL2Interleukin-6Interleukin-8Ligandscecumcorrelation analysisEimeria tenellagene expressionspleen

Identifiers

PMID32115023
PMCPMC7587758
OpenAlexW2996396456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.