Evidence map›Paper›PMID 32115002›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2020

Mental disorders and total mortality after 20 years in an adult general population sample.

Ulrich John, Hans-Jürgen Rumpf, Monika Hanke, Christian Meyer

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ulrich JohnDepartment of Social Medicine and Prevention, Institute of Community Medicine, University Medicine Greifswald, Greifswald, Germany.ORCID 0000-0003-0587-5298
Hans-Jürgen RumpfDepartment of Psychiatry and Psychotherapy, Research Group S:TEP, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-6848-920X
Monika HankeDepartment of Social Medicine and Prevention, Institute of Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Christian MeyerDepartment of Social Medicine and Prevention, Institute of Community Medicine, University Medicine Greifswald, Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneral population data on associations between mental disorders and total mortality are rare. The aim was to analyze whether the number of mental disorders, single substance use, mood, anxiety, somatoform or eating disorders during the lifetime and whether treatment utilization may predict time to death 20 years later in the general adult population.

methodsWe used data from the Composite International Diagnostic Interview, which includes DSM-IV diagnoses for substance use, mood, anxiety, somatoform, and eating disorders, for a sample of 4,075 residents in Germany who were 18-64 years old in 1996. Twenty years later, mortality was ascertained using the public mortality database for 4,028 study participants. Cox proportional hazards models were applied for disorders that existed at any time in life before the interview.

resultsThe data revealed increased hazard ratios (HRs) for number of mental disorders (three or more; HR 1.4; 95% confidence interval [CI] 1.1-1.9) and for single disorders (alcohol dependence, dysthymia, panic disorder with agoraphobia, and hypochondriasis), with the reference group being study participants who had not suffered from any of the mental disorders analyzed and with adjustments made for age, sex, and education. Among individuals with any mental disorder during their lifetimes, having been an inpatient in treatment for a mental disorder was related to a higher HR (2.2; CI 1.6-3.0) than was not having been in any treatment for a mental disorder.

conclusionsIn this sample of adults in the general population, three or more mental disorders, alcohol dependence, dysthymia, panic disorder with agoraphobia, and hypochondriasis were related to premature death.

Indexed as

Life StyleAdultAgedAged, 80 and overAlcoholismAnxiety DisordersDiagnostic and Statistical Manual of Mental DisordersFemaleGermanyHumansMaleMental DisordersMental HealthMiddle AgedPanic DisorderSubstance-Related DisordersAffective disordersanxiety disordersgeneral populationmortalitysomatoform disorderssubstance use disorders

Identifiers

PMID32115002
PMCPMC7315884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.