Evidence map›Paper›PMID 32114964›Full record

ArticleJournal of chemotherapy (Florence, Italy)2020

Assessment of antimicrobial use and prescribing practices among pediatric inpatients in Zimbabwe.

Ioana D Olaru, Anne Meierkord, Brian Godman, Crispen Ngwenya, Felicity Fitzgerald, Vongai Dondo, Rashida A Ferrand, Katharina Kranzer

Open access · greenAbstract read
In one paragraph

Article in Journal of chemotherapy (Florence, Italy), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Ioana D OlaruLondon School of Hygiene and Tropical Medicine, Bloomsbury, London, UK.
Anne MeierkordLondon School of Hygiene and Tropical Medicine, Bloomsbury, London, UK.
Brian GodmanStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Crispen NgwenyaFaculty of Medicine, Department of Paediatrics, Midlands State University, Gweru, Zimbabwe.
Felicity FitzgeraldBiomedical Research and Training Institute, Avondale, Harare, Zimbabwe.
Vongai DondoDepartment of Pediatrics, Harare Central Hospital, Harare, Zimbabwe.
Rashida A FerrandLondon School of Hygiene and Tropical Medicine, Bloomsbury, London, UK.
Katharina KranzerLondon School of Hygiene and Tropical Medicine, Bloomsbury, London, UK.
Biomedical Research and Training Institute · ZWLondon School of Hygiene & Tropical Medicine · GBHarare Central Hospital · ZWKarolinska University Hospital · SEMidlands State University · ZWUniversity College London · GB

Funding

Wellcome Trust 206316/Z/17/Z
6 · The paper itself

Abstract

This study aims to assess antimicrobial consumption in the pediatric department of a tertiary care public hospital in Zimbabwe. Clinical records of pediatric inpatients admitted to Harare Central Hospital over a 3-week period were reviewed prospectively. Antimicrobial consumption was described as days of therapy per 100 inpatient days (DOT/100 PD). Adherence of antimicrobial drug prescriptions to the National Guidelines was also evaluated. A total of 121 (93.1%) children were prescribed at least one antimicrobial out of 130 children admitted. The median age was 14 months (IQR: 3 - 48 months). Overall antimicrobial consumption was 155.4 DOT/100 PD (95% CI 146-165.2). The most frequently prescribed antimicrobials were benzylpenicillin, gentamicin and ceftriaxone. Prescriptions were adherent to national guidelines in 57.7% of children. This study shows that there is high antimicrobial drug usage in hospitalized children in Zimbabwe and a considerable proportion of prescriptions are non-adherent with national guidelines.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipChildChild, PreschoolDrug UtilizationFemaleGuideline AdherenceHumansInfantInfant, NewbornInpatientsMalePractice Guidelines as TopicPractice Patterns, Physicians'Tertiary Care CentersZimbabweAnti-Bacterial AgentsAMRAntibiotic resistanceAntimicrobial consumptionAntimicrobial resistanceAntimicrobial stewardshipChildren

Identifiers

PMID32114964
PMCPMC7614934
OpenAlexW3010036300

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.