Evidence map›Paper›PMID 32114682›Full record

ArticleAnnals of nuclear medicine2020

Three-dimensional Monte Carlo-based voxel-wise tumor dosimetry in patients with neuroendocrine tumors who underwent

Th I Goetz, E W Lang, O Prante, A Maier, M Cordes, T Kuwert, P Ritt, Christian Schmidkonz

Open access · hybridAbstract read
In one paragraph

Article in Annals of nuclear medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Deep transformer-based personalized dosimetry from SPECT/CT images: a hybrid approach for [European journal of nuclear medicine and molecular imaging · 2024
    Article
  6. Tumor dosimetry usingEJNMMI physics · 2023
    Article
  7. Review
  8. Voxel-Based Internal Dosimetry forNuclear medicine and molecular imaging · 2023
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Th I GoetzDepartment of Nuclear Medicine, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
E W LangBiophysics, University of Regensburg, Regensburg, Germany.
O PranteDepartment of Nuclear Medicine, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
A MaierPattern Recognition Lab, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
M CordesDepartment of Nuclear Medicine, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
T KuwertDepartment of Nuclear Medicine, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
P RittDepartment of Nuclear Medicine, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Christian SchmidkonzDepartment of Nuclear Medicine, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany. christian.schmidkonz@uk-erlangen.de.ORCID http://orcid.org/0000-0002-1988-0058
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with advanced neuroendocrine tumors (NETs) of the midgut are suitable candidates for

methodsA cohort of 14 patients with histologically confirmed metastasized NETs of the midgut (11 men, 3 women, 62.3 ± 11.0 years of age) underwent a total of 39 cycles of

resultsThe average dose values per cycle were 3.41 ± 1.28 Gy (1.91-6.22 Gy) for the kidneys, 4.40 ± 2.90 Gy (1.14-11.22 Gy) for the spleen, and 9.70 ± 8.96 Gy (1.47-39.49 Gy) for all

conclusionThese results suggest that Monte Carlo-based voxel-wise dosimetry is a very promising tool for predicting the absorbed TTD based on histological and clinical parameters.

Indexed as

AgedAntineoplastic AgentsChromogranin AFemaleHumansLutetiumMaleMiddle AgedMonte Carlo MethodNeuroendocrine TumorsOctreotideOrganometallic CompoundsRadioisotopesRadiometryRadiopharmaceuticalsRadiotherapy DosageAntineoplastic AgentsChromogranin AEdotreotideedotreotide lutetium LU-177LutetiumLutetium-177OctreotideOrganometallic CompoundsRadioisotopesRadiopharmaceuticals177Lu-DOTATOCDosimetryMonte Carlo simulationsNeuroendocrine tumors

Identifiers

PMID32114682
PMCPMC7101301
OpenAlexW3008646208

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.