Evidence map›Paper›PMID 32114485›Full record

ArticleBMJ open diabetes research & care2020

Role of the DNA repair genes

Kerstin Rohde, Torunn Rønningen, Lars la Cour Poulsen, Maria Keller, Matthias Blüher, Yvonne Böttcher

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Metabolic Syndrome and Autophagy: Focus on HMGB1 Protein.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kerstin RohdeLeipzig University Medical Center, IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Torunn RønningenDepartment of Clinical Molecular Biology, Akershus University Hospital, Lørenskog, Norway.
Lars la Cour PoulsenDepartment of Clinical Molecular Biology, Akershus University Hospital, Lørenskog, Norway.
Maria KellerLeipzig University Medical Center, IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Matthias BlüherLeipzig University Medical Center, IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Yvonne BöttcherLeipzig University Medical Center, IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany yvonne.bottcher@medisin.uio.no.ORCID 0000-0002-9775-425X
Akershus University Hospital · NOIFB Adiposity Diseases · DEUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRegional fat distribution strongly relates to metabolic comorbidities. We identified the DNA repair genes RESEARCH DESIGN AND

methodsGene expression (OVAT n=48; SAT n=55) and DNA promoter methylation data (OVAT and SAT n=77) were extracted from an existing dataset as described elsewhere. Genotype data for the 3'untranslated region (3'UTR)

resultsWe identified

conclusionOur results suggest a fat depot-specific regulation of

Indexed as

Gene Expression3' Untranslated RegionsAdiposityAdultAgedAllelesCohort StudiesDNA MethylationDNA RepairFemaleGenetic LociGenotypeHistonesHMGB1 ProteinHumansIntra-Abdominal Fat3' Untranslated RegionsH2AX protein, humanHistonesHMGB1 ProteinHMGB1 protein, humanRNA, Messengerfat distributionmetabolic syndromeobesity and body fat distributiontranscription

Identifiers

PMID32114485
PMCPMC7050360
OpenAlexW3006807419

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.