Evidence map›Paper›PMID 32114474›Full record

ArticleBMJ open2020

Effects of medical and non-medical cannabis use in older adults: protocol for a scoping review.

Dianna Wolfe, Kimberly Corace, Danielle Rice, Andra Smith, Salmaan Kanji, David Conn, Melanie Willows, Gary E Garber, John Puxty, Esther Moghadam and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Dianna Wolfe *Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Kimberly Corace *Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Danielle RiceClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Andra SmithBrain and Mind Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
Salmaan KanjiClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
David ConnDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Melanie WillowsInstitute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada.
Gary E GarberClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
John PuxtyFaculty of Medicine, Queen's University, Kingston, Ontario, Canada.
Esther MoghadamHealth Promotion, Ottawa Public Health, Ottawa, Ontario, Canada.
Becky SkidmoreClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Chantelle GarrittyClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Kednapa ThavornClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
David MoherClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID 0000-0003-2434-4206
Brian HuttonClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada bhutton@ohri.ca.ORCID 0000-0001-5662-8647
University of Ottawa · CAOttawa Hospital · CAOttawa Public Health · CAQueen's University · CAUniversity of Toronto · CA

Funding

CIHR
6 · The paper itself

Abstract

introductionWith its legalisation and regulation in Canada in 2018, the proportion of Canadians reporting cannabis use in 2019 increased substantially over the previous year, with half of new users being aged 45+ years. While use in older adults has been low historically, as those born in the 1950s and 1960s continue to age, this demographic will progressively have more liberal attitudes, prior cannabis exposure and higher use rates. However, older adults experience slower metabolism, increased likelihood of polypharmacy, cognitive decline and chronic physical/mental health problems. There is a need to enhance knowledge of the effects of cannabis use in older adults. The following question will be addressed using a scoping review approach: what evidence exists regarding beneficial and harmful effects of medical and non-medical cannabis use in adults >50 years of age? Given that beneficial and harmful effects of cannabis may be mediated by patient-level (eg, age, sex and race) and cannabis-related factors (eg, natural vs synthetic, consumption method), subgroup effects related to these and additional factors will be explored. METHODS AND ANALYSIS: Methods for scoping reviews outlined by Arksey & O'Malley and the Joanna Briggs Institute will be used. A librarian designed a systematic search of the literature from database inception to June 2019. Using the OVID platform, Ovid MEDLINE will be searched, including Epub Ahead of Print and In-Process and Other Non-Indexed Citations, Embase Classic+Embase, and PsycINFO for reviews, randomised trials, non-randomised trials and observational studies of cannabis use. The Cochrane Library on Wiley will also be searched. Eligibility criteria will be older adult participants, currently using cannabis (medical or non-medical), with studies required to report a cannabis-related health outcome to be eligible. Two reviewers will screen citations and full texts, with support from artificial intelligence. Two reviewers will chart data. Tables/graphics will be used to map evidence and identify evidence gaps. ETHICS AND DISSEMINATION: This research will enhance awareness of existing evidence addressing the health effects of medical and non-medical cannabis use in older adults. Findings will be disseminated through a peer-reviewed publication, conference presentations and a stakeholder meeting. TRIAL REGISTRATION NUMBER: DOI 10.17605/OSF.IO/5JTAQ.

Indexed as

Marijuana AbuseMarijuana UseMedical MarijuanaAgedAged, 80 and overAge FactorsCanadaHumansScoping Reviews as TopicMedical Marijuanaepidemiologygeriatric medicinepublic health

Identifiers

PMID32114474
PMCPMC7050329
OpenAlexW3006853591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.