Evidence map›Paper›PMID 32114452›Full record

ArticleFrontiers in bioscience (Scholar edition)2020

Role of natural compounds in preventing and treating breast cancer.

Brianna Noel, Santosh Kumar Singh, James W Lillard, Rajesh Singh

Open access · bronzeAbstract read
In one paragraph

Article in Frontiers in bioscience (Scholar edition), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brianna NoelMorehouse School of Medicine, 720 Westview Drive SW, Atlanta GA 30310.
Santosh Kumar SinghDepartment of Microbiology, Biochemistry and Immunology,Morehouse School of Medicine, 720 Westview drive, SW, Atlanta- 30310 USA.
James W LillardMorehouse School of Medicine, 720 Westview Drive SW, Atlanta GA 30310.
Rajesh SinghMorehouse School of Medicine, 720 Westview Drive SW, Atlanta, rsingh@msm.edu.
Morehouse School of Medicine · US

Funding

Research Training & Career Development ProgramU54CA118638 · NCI · MOREHOUSE SCHOOL OF MEDICINE · PI Desiree Avia Rivers · 2005 to 2026
$22.7M
Targeted Nanotherapy for prostate cancerSC1CA193758 · NCI · MOREHOUSE SCHOOL OF MEDICINE · PI SINGH, RAJESH · 2014 to 2017
$1.4M
NCI NIH HHS SC1 CA193758NCI NIH HHS U54 CA118638
6 · The paper itself

Abstract

Breast cancer (BrCa) is the most commonly diagnosed cancer and the second leading cause of cancer-related death in women. Alarming increases in the cases quests for more effective treatment of BrCa. As most chemotherapeutic drugs are associated with drug resistance, cancer relapse, and side effects, scientists are turning to agents with more efficacy, such as natural compounds for treatment and prevention of BrCa. Selected natural compounds, substances derived from living organisms, promote apoptosis and inhibit metastasis, preventing cancer growth. As a result, these compounds have the potential to suppress BrCa progression, thus increasing patient survival rates and decreasing the number of BrCa-related deaths. In this review, we summarize natural compounds that have displayed, anti-cancer effects on BrCa cells in various studies. These natural compounds inhibit the development of BrCa, suppress the growth of cancer cells, and promote cell death. We conclude that natural compounds are efficient, effective and promising agents for treating BrCa other than therapeutic methods.

Indexed as

AnimalsApoptosisBiological ProductsBreast NeoplasmsFemaleHumansPlant ExtractsBiological ProductsPlant Extracts

Identifiers

PMID32114452
PMCPMC7326582
OpenAlexW3007269532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.