Evidence map›Paper›PMID 32114145›Full record

ArticleBrain and language2020

Neuroanatomical correlates of phonologic errors in logopenic progressive aphasia.

Diana Petroi, Joseph R Duffy, Andrew Borgert, Edythe A Strand, Mary M Machulda, Matthew L Senjem, Clifford R Jack, Keith A Josephs, Jennifer L Whitwell

Open access · greenAbstract read
In one paragraph

Article in Brain and language, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  8. Article
  9. Phonological Errors in Posterior Cortical Atrophy.Dementia and geriatric cognitive disorders · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Diana PetroiDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: morningglory103@gmail.com.
Joseph R DuffyDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Andrew BorgertDepartment of Medical Research, Gundersen Health System, La Crosse, WI 54601, USA.
Edythe A StrandDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Mary M MachuldaDepartment of Psychology and Psychiatry, Mayo Clinic, Rochester, MN 55905, USA.
Matthew L SenjemDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA; Department of Information Technology, Mayo Clinic, Rochester, MN 55905, USA.
Clifford R JackDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: Whitwell.jennifer@mayo.edu.
WinnMed · USGundersen Health System · USMayo Clinic · USMayo Clinic in Arizona · US

Funding

Molecular and structural imaging in atypical Alzheimer's disease: a longitudinal studyR01AG050603 · NIA · MAYO CLINIC ROCHESTER · PI WHITWELL, JENNIFER LOUISE · 2016 to 2025
$5.9M
PIB PET Scanning in Speech and Language Based DementiasR01DC010367 · NIDCD · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2010 to 2014
$1.7M
NIA NIH HHS R01 AG050603NIDCD NIH HHS R01 DC010367
6 · The paper itself

Abstract

While phonologic errors may be one of the salient features of the logopenic variant of primary progressive aphasia (lvPPA), sparse data are available on their neuroimaging correlates. The purpose of this study was to identify brain regions associated with different types of phonologic errors across several tasks for participants with lvPPA. Correlational analyses between phonologic errors across tasks most likely to elicit such errors and specific left hemisphere gray matter volume regions were conducted for 20 participants. Findings point to the inferior parietal lobe and supramarginal gyrus as being the most relevant correlates. Atrophy in these regions may increase the likelihood of making phonologic errors in lvPPA, particularly substitution error types. Our results provide support for neuroanatomical correlates of phonologic errors in the parietal region, which is consistent with previous findings of temporoparietal cortex involvement/atrophy in lvPPA.

Indexed as

AgedAphasia, Primary ProgressiveBrainBrain MappingFemaleGray MatterHumansMaleMiddle AgedLogopenic progressive aphasiaNeuroanatomical correlatesNeuroimagingPhonologic errorsPrimary progressive aphasia

Identifiers

PMID32114145
PMCPMC7219283
OpenAlexW3008298719

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.