Evidence map›Paper›PMID 32113974›Full record

ArticleArchives of physical medicine and rehabilitation2020

Survivors of Chronic Stroke Experience Continued Impairment of Dexterity But Not Strength in the Nonparetic Upper Limb.

Alexander J Barry, Kristen M Triandafilou, Mary Ellen Stoykov, Naveen Bansal, Elliot J Roth, Derek G Kamper

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05929027 (Self-Administered Gaming and Exercise at Home), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05929027 narecruitingnot on this mapstarted 2023, after this paper: background citation

Self-Administered Gaming and Exercise at Home (SAGEH)

TypeinterventionalSponsorJohns Hopkins UniversityRan2023 to 2027Enrolled60ConditionsStroke, Hand WeaknessArmsNoNo, occupational therapy - self directed
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. AI in Medical Questionnaires: Scoping ReviewJournal of medical Internet research · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Roles of Handedness and Hemispheric Lateralization: Implications for Rehabilitation of the Central and Peripheral Nervous Systems: A Rapid Review.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2024
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alexander J BarryShirley Ryan AbilityLab, Chicago, Illinois. Electronic address: abarry@sralab.org.
Kristen M TriandafilouShirley Ryan AbilityLab, Chicago, Illinois.
Mary Ellen StoykovShirley Ryan AbilityLab, Chicago, Illinois.
Naveen BansalDepartment of Mathematical and Statistical Sciences, Marquette University, Milwaukee, Wisconsin.
Elliot J RothShirley Ryan AbilityLab, Chicago, Illinois; Department of Physical Medicine & Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Derek G KamperDepartment of Physical Medicine & Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, Illinois; UNC/NC State Joint Department of Biomedical Engineering, North Carolina State University, Raleigh, North Carolina; Closed-Loop Engineering for Advanced Rehabilitation Research Core, North Carolina State University, Raleigh, North Carolina.
Shirley Ryan AbilityLab · USMarquette University · USNorth Carolina State University · USNorthwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Altering Activation Patterns in the Distal Upper Extremity After StrokeR01HD075813 · NICHD · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI ROTH, ELLIOT J. · 2014 to 2019
$1.9M
NCATS NIH HHS UL1 TR001422NICHD NIH HHS R01 HD075813
6 · The paper itself

Abstract

objectiveTo investigate the performance of the less affected upper limb in people with stroke compared with normative values. To examine less affected upper limb function in those whose prestroke dominant limb became paretic and those whose prestroke nondominant limb became paretic.

designCohort study of survivors of chronic stroke (7.2±6.7y post incident).

settingThe study was performed at a freestanding academic rehabilitation hospital.

participantsSurvivors of chronic stroke (N=40) with severe hand impairment (Chedoke-McMaster Stroke Assessment rating of 2-3 on Stage of Hand) participated in the study. In 20 participants the prestroke dominant hand (DH) was tested (nondominant hand [NH] affected by stroke), and in 20 participants the prestroke NH was tested (DH affected by stroke).

interventionsNot applicable.

main outcome measureJebsen-Taylor Hand Function Test. Data from survivors of stroke were compared with normative age- and sex-matched data from neurologically intact individuals.

resultsWhen combined, DH and NH groups performed significantly worse on fine motor tasks with their nonparetic hand relative to normative data (P<.007 for all measures). Even the participants who continued to use their prestroke DH as their primary hand after the stroke demonstrated reduced fine motor skills compared with normative data. In contrast, grip strength was not significantly affected in either group of survivors of stroke (P>.140).

conclusionsSurvivors of stroke with severe impairment of the paretic limb continue to present significant upper extremity impairment in their nominally nonparetic limb even years after stroke. This phenomenon was observed regardless of whether the DH or NH hand was primarily affected. Because this group of survivors of stroke is especially dependent on the nonparetic limb for performing functional tasks, our results suggest that the nonparetic upper limb should be targeted for rehabilitation.

Indexed as

Disability EvaluationAcademic Medical CentersAgedChronic DiseaseCohort StudiesCross-Sectional StudiesExercise TestFemaleHand StrengthHumansMaleMiddle AgedParesisPrognosisReference ValuesRehabilitation CentersFunctional lateralityRecovery of functionRehabilitationStrokeStroke rehabilitation

Identifiers

PMID32113974
PMCPMC7311247
OpenAlexW3007911708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.