Evidence map›Paper›PMID 32113348›Full record

ArticleThe Journal of chemical physics2020

Nucleation and shape dynamics of model nematic tactoids around adhesive colloids.

Nicholas B Ludwig, Kimberly L Weirch, Eli Alster, Thomas A Witten, Margaret L Gardel, Kinjal Dasbiswas, Suriyanarayanan Vaikuntanathan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of chemical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicholas B LudwigDepartment of Chemistry and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637, USA.ORCID 000000027345659X
Kimberly L WeirchPritzker School of Molecular Engineering, The University of Chicago, Chicago, Illinois 60637, USA.ORCID 0000000304408612
Eli AlsterDepartment of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, USA.ORCID 0000000184215911
Thomas A WittenDepartment of Physics and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637, USA.
Margaret L GardelDepartment of Physics and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637, USA.ORCID 0000000318469854
Kinjal DasbiswasDepartment of Physics, University of California, Merced, Merced, California 95343, USA.
Suriyanarayanan VaikuntanathanDepartment of Chemistry and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637, USA.ORCID 0000000324316045

Funding

Mechanical Regulation of Cell Adhesion by Dynamic Cytoskeletal Assemblies - Resubmission 01R01GM104032 · NIGMS · UNIVERSITY OF CHICAGO · PI GARDEL, MARGARET LISE · 2015 to 2023
$2.5M
NIGMS NIH HHS R01 GM104032
6 · The paper itself

Abstract

Recent experiments have shown how nematically ordered tactoid shaped actin droplets can be reorganized and divided by the action of myosin molecular motors. In this paper, we consider how similar morphological changes can potentially be achieved under equilibrium conditions. Using simulations, both atomistic and continuum, and a simple macroscopic model, we explore how the nucleation dynamics, shape changes, and the final steady state of a nematic tactoid droplet can be modified by interactions with model adhesive colloids that mimic a myosin motor cluster. We show how tactoid reorganization may occur in an equilibrium colloidal-nematic setting. We then suggest based on the simple macroscopic model how the simulation models may be extended to potentially stabilize divided tactoids.

Indexed as

Molecular Dynamics SimulationAdhesivesColloidsMyosinsParticle SizeSurface PropertiesAdhesivesColloidsMyosins

Identifiers

PMID32113348
PMCPMC13074159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.