Evidence map›Paper›PMID 32112633›Full record

ArticleInternational journal of fertility & sterility2020

Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience.

Dalia Khalife, Anwar Nassar, Ali Khalil, Johnny Awwad, Antoine Abu Musa, Antoine Hannoun, Lina El Taha, Fatin Khalifeh, May Abiad, Ghina Ghazeeri

Abstract read
In one paragraph

Article in International journal of fertility & sterility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dalia KhalifeDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Anwar NassarDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Ali KhalilDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Johnny AwwadDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Antoine Abu MusaDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Antoine HannounDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Lina El TahaDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Fatin KhalifehDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
May AbiadFaculty of Medicine, American University of Beirut, Beirut, Lebanon.
Ghina GhazeeriDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon. Electronic Address: gg02@aub.edu.lb.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this retrospective study is to investigate the cumulative live birth rate (CLBR) following one or more completed MATERIALS AND

methodsIn this retrospective study, five hundred forty-seven women who received 736 fresh ovarian stimulation/embryo transfer cycles between January 2016 and December 2016 were included in the study at a tertiary care center located in Lebanon.

resultsIn all women, the live birth rate for the first cycle was 33.0% [95% confidence interval (CI): 27.8-38.2]. The CLBR showed an increase with each successive fresh cycle to reach 56.9% (95% CI: 51.2-62.4) after 3 cycles and 67.9% (95% CI: of 62.5-73.0) after 6 cycles. The CLBR following 6 cycles reached 69.9% (95% CI: 63.8-75.6) in women younger than 35 years. In women older than 40 years, however, the live birth rate for the first cycle was significantly low at 3.1% (95% CI: 0.3-9.5) with a plateau in success rates after 4 cycles reaching 21.9% (95% CI: 9.2-40.0). Couples with different types of infertility had CLBRs ranging from 65% to 72%, with the exception of women with low ovarian reserve, where CLBRs reached 29.4% (95% CI: 10.3-56.0).

conclusionThe CLBR at a referral center in a Middle Eastern country reached 67.9 % after 6 cycles, with variations by age and type of infertility treatment. These findings are encouraging for patients insisting to extend their treatment beyond 4 to 5 cycles.

Indexed as

Assisted Reproductive TechniquesLive Birth Pregnancy RateMaternal AgeMultiple Pregnancy

Identifiers

PMID32112633
PMCPMC7139227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.