Evidence map›Paper›PMID 32112462›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2020

Burden of disease of type 2 diabetes mellitus: cost of illness and quality of life estimated using the Maastricht Study.

L M M Janssen, M Hiligsmann, A M J Elissen, M A Joore, N C Schaper, J H A Bosma, C D A Stehouwer, S J S Sep, A Koster, M T Schram and 1 more

Abstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Investigating the Antidiabetic Effects ofFood science & nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

L M M JanssenDepartment of Health Services Research, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0002-0184-3742
M HiligsmannDepartment of Health Services Research, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-4274-9258
A M J ElissenDepartment of Health Services Research, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-9795-8095
M A JooreDepartment of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0002-5649-6768
N C SchaperDepartment of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0002-2128-8029
J H A BosmaDepartment of Social Medicine, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-4333-4564
C D A StehouwerDepartment of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0001-8752-3223
S J S SepDepartment of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
A KosterDepartment of Social Medicine, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-1583-7391
M T SchramDepartment of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0001-8113-7604
S M A A EversDepartment of Health Services Research, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-1026-570X

Funding

CAPHRI Care and Public Health Research Institute (Maastricht, The Netherlands)CARIM School for Cardiovascular Diseases (Maastricht, The Netherlands)European Regional Development Fund via OP-Zuid, the Province of Limburg, the Dutch Ministry of Economic Affairs (grant 31O.041)Health Foundation Limburg (Maastricht, The Netherlands)Janssen-Cilag B.V. (Tilburg, The Netherlands)Novo Nordisk Farma B.V. (Alphen aan den Rijn, The Netherlands)NUTRIM School for Nutrition and Translational Research in Metabolism (Maastricht, The Netherlands)Sanofi-Aventis Netherlands B.V. (Gouda, The Netherlands)Stichting Annadal (Maastricht, The Netherlands)Stichting De Weijerhorst (Maastricht, The Netherlands)the Cardiovascular Center (CVC, Maastricht, the Netherlands)the Pearl String Initiative Diabetes (Amsterdam, The Netherlands)
6 · The paper itself

Abstract

aimsTo estimate the societal costs and quality of life of people with type 2 diabetes and to compare these results with those of people with normal glucose tolerance or prediabetes.

methodsData from 2915 individuals from the population-based Maastricht Study were included. Costs were assessed through a resource-use questionnaire completed by the participants; cost prices were based on Dutch costing guidelines. Quality of life was expressed in utilities using the Dutch EuroQol 5D-3L questionnaire and the SF-36 health survey. Based on normal fasting glucose and 2-h plasma glucose values, participants were classified into three groups: normal glucose tolerance (n = 1701); prediabetes (n = 446); or type 2 diabetes (n = 768).

resultsParticipants with type 2 diabetes had on average 2.2 times higher societal costs than those with normal glucose tolerance (€3,006 and €1,377 per 6 months, respectively) and had lower utilities (0.77 and 0.81, respectively). No significant differences were found between participants with normal glucose tolerance and those with prediabetes. Subgroup analyses showed that higher age, being female and having two or more diabetes-related complications resulted in higher costs (P < 0.05) and lower utilities.

conclusionsThis study showed that people with type 2 diabetes have substantially higher societal costs and lower quality of life than people with normal glucose tolerance. The results provide important input for future model-based economic evaluations and for policy decision-making.

Indexed as

Cost of IllnessHealth Care CostsQuality of LifeAdultAgedCase-Control StudiesDiabetes Mellitus, Type 2FemaleHumansLinear ModelsMaleMiddle AgedNetherlandsPrediabetic State

Identifiers

PMID32112462
PMCPMC7539911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.