Evidence map›Paper›PMID 32112386›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2020

Stem Cell Tracking with Nanoparticle-Based Ultrasound Contrast Agents.

Fang Chen, Jesse V Jokerst

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. International journal of stem cells · 2023
    Review
  4. Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2023
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fang ChenDepartment of Nanoengineering, Materials Science and Engineering Program, University of California, San Diego, CA, USA. fachen@eng.ucsd.edu.
Jesse V JokerstDepartment of Nanoengineering, Materials Science and Engineering Program, University of California, San Diego, CA, USA.

Funding

Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
A Therapeutic Tool for Ultrasound-Guided Stem Cell TherapyR00HL117048 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2015 to 2017
$747k
NHLBI NIH HHS DP2 HL137187NHLBI NIH HHS R00 HL117048
6 · The paper itself

Abstract

Cell therapy is revolutionizing modern medicine. To promote this emerging therapy, the ability to image and track therapeutic cells is critical to monitor the progress of the treatment. Ultrasound imaging is promising in tracking therapeutic cells but suffers from poor contrast against local tissues. Therefore, it is critical to increase the ultrasound contrast of therapeutic cells over local tissue at the injection site. Here, we describe a method to increase the ultrasound intensity of therapeutic cells with nanoparticles to make the injected therapeutic cells more visible.

Indexed as

Cell TrackingContrast MediaHumansMagnetic Resonance ImagingMesenchymal Stem CellsNanoparticlesUltrasonographyContrast MediaCell trackingContrast agentsMesenchymal stem cellsNanoparticlesUltrasound imaging

Identifiers

PMID32112386
PMCPMC8045894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.