Evidence map›Paper›PMID 32112345›Full record

ReviewCurrent heart failure reports2020

The Heart Failure with Preserved Ejection Fraction Conundrum-Redefining the Problem and Finding Common Ground?

P Iyngkaran, M C Thomas, C Neil, M Jelinek, M Cooper, J D Horowitz, D L Hare, D M Kaye

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current heart failure reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

P IyngkaranWerribee Mercy Sub School, School of Medicine, Sydney, Australia.
M C ThomasBiochemistry of Diabetes Complications, Melbourne, Australia.
C NeilDepartment of Medicine-Western Precinct, University of Melbourne, Melbourne, Victoria, 3011, Australia.
M JelinekDepartment of Cardiology, St. Vincent's Hospital, Melbourne, Victoria, Australia.
M CooperDepartment of Diabetes, The Alfred and Monash University, Melbourne, Australia.
J D HorowitzCardiology University of Adelaide, Adelaide, 5011, Australia.
D L HareCardiovascular Research, Heart Failure Services, Austin Health, University of Melbourne, Melbourne, Victoria, Australia.
D M KayeCardiology and Head Heart Failure Research, Alfred Hospital, Melbourne, Australia. d.kaye@alfred.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHeart failure with preserved ejection fraction (HFpEF) or diastolic heart failure (DHF) makes up more than half of all congestive heart failure presentations (CHF). With an ageing population, the case load and the financial burden is projected to increase, even to epidemic proportions. CHF hospitalizations add too much of the financial and infrastructure strain. Unlike systolic heart failure (SHF), much is still either uncertain or unknown. Specifically, in epidemiology, the disease burden is established; however, risk factors and pathophysiological associations are less clear; diagnostic tools are based on rigid parameters without the ability to accurately monitor treatments effects and disease progression; finally, therapeutics are similar to SHF but without prognostic data for efficacy. RECENT

findingsThe last several years have seen guidelines changing to account for greater epidemiological observations. Most of these remain general observation of shortness of breath symptom matched to static echocardiographic parameters. The introduction of exercise diastolic stress test has been welcome and warrants greater focus. HFpEF is likely to see new thinking in the coming decades. This review provides some of perspective on this topic.

Indexed as

EchocardiographyExercise TestHeart Failure, DiastolicHumansStroke VolumeVentricular Function, LeftClinical trialsDiagnosisDiastolic heart failureEpidemiologyHeart failure with preserved ejection fractionHFpEF

Identifiers

PMID32112345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.