Evidence map›Paper›PMID 32112295›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Anxiety and hemodynamic reactivity during cardiac stress testing: The role of gender and age in myocardial ischemia.

Maria T Bekendam, Paula M C Mommersteeg, Willem J Kop, Jos W Widdershoven, Ilse A C Vermeltfoort

Registry-linked trialOpen access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05896982 (Optimizing Patient Experience During Myocardial Perfusion Imaging), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05896982 nacompletednot on this mapstarted 2022, after this paper: background citation

Optimizing Patient Experience During Myocardial Perfusion Imaging

TypeinterventionalSponsorTilburg UniversityRan2022 to 2024Enrolled149ConditionsMyocardial Ischemia, Myocardial Infarction, Autonomic DysfunctionArmsCare as usual with information support, Care as usual with supportive coaching, Care as usual with information support and supportive coaching
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Article
  5. Article
  6. Psychological factors of suspect coronary microvascular dysfunction in patients undergoing SPECT imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Anxiety as a risk factor in coronary artery disease among young women.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Maria T BekendamDepartment of Medical and Clinical Psychology, Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Warandelaan 2, P.O. Box 90153, 5037 AB, Tilburg, The Netherlands.
Paula M C MommersteegDepartment of Medical and Clinical Psychology, Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Warandelaan 2, P.O. Box 90153, 5037 AB, Tilburg, The Netherlands. p.m.c.mommersteeg@tilburguniversity.edu.
Willem J KopDepartment of Medical and Clinical Psychology, Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Warandelaan 2, P.O. Box 90153, 5037 AB, Tilburg, The Netherlands.
Jos W WiddershovenDepartment of Medical and Clinical Psychology, Center of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, Warandelaan 2, P.O. Box 90153, 5037 AB, Tilburg, The Netherlands.
Ilse A C VermeltfoortDepartment of Nuclear Medicine, Institute Verbeeten, Tilburg, The Netherlands.
Tilburg University · NLElisabeth-TweeSteden Ziekenhuis · NLInstituut Verbeeten · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of myocardial ischemia is associated with anxiety. State and trait anxiety are more common in younger women compared to men, and high anxiety levels could affect hemodynamic reactivity during cardiac stress testing. The aim is to examine whether anxiety plays a role in gender differences in patients ≤ 65 and > 65 years in hemodynamic reactivity and ischemia during cardiac stress testing. METHODS AND

resultsIncluded were 291 patients (66.8 ± 8.7 years, 45% women) with suspect ischemia undergoing myocardial perfusion single-photon emission computed tomography (MPI-SPECT). Primary outcomes were semi-quantitative summed difference score (SDS) and summed stress score (SSS), as continuous indicators of myocardial ischemia. Analyses were stratified by age. Trait anxiety was measured using a validated questionnaire (GAD-7) and state anxiety using facial expression analyses software. Overall, trait and state anxiety were not associated with the prevalence of ischemia (N = 107, 36%). A significant interaction was found between gender and trait anxiety in women ≤ 65 years for SDS (F(1,4) = 5.73, P = .019) and SSS (F(1,10) = 6.50, P = .012). This was not found for state anxiety.

conclusionSDS and SSS were significantly higher in women younger than 65 years with high trait anxiety. This interaction was not found in men and women over 65 years.

Indexed as

HemodynamicsAgedAge FactorsAnxietyExercise TestFemaleHumansMaleMiddle AgedMyocardial IschemiaSex FactorsAgeCardiac stress testingMyocardial ischemiaSex differencesTrait anxiety

Identifiers

PMID32112295
PMCPMC8709819
OpenAlexW3007230625

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.