Evidence map›Paper›PMID 32112256›Full record

ArticleCell and tissue research2020

Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon.

Monika L Bayer, Rene B Svensson, Peter Schjerling, Ashley S Williams, David H Wasserman, Michael Kjaer

Abstract read
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In one paragraph

Article in Cell and tissue research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Monika L BayerInstitute of Sports Medicine Copenhagen, Department of Orthopedic Surgery M, Bispebjerg Hospital, Nielsine Nielsenvej 11, 2400, Copenhagen NV, Denmark. Monika.lucia.bayer@regionh.dk.ORCID http://orcid.org/0000-0002-6720-6543
Rene B SvenssonInstitute of Sports Medicine Copenhagen, Department of Orthopedic Surgery M, Bispebjerg Hospital, Nielsine Nielsenvej 11, 2400, Copenhagen NV, Denmark.
Peter SchjerlingInstitute of Sports Medicine Copenhagen, Department of Orthopedic Surgery M, Bispebjerg Hospital, Nielsine Nielsenvej 11, 2400, Copenhagen NV, Denmark.
Ashley S WilliamsDepartment of Molecular Physiology and Biophysics, Vanderbilt University, 823 Light Hall, Nashville, TN, USA.
David H WassermanDepartment of Molecular Physiology and Biophysics, Vanderbilt University, 823 Light Hall, Nashville, TN, USA.
Michael KjaerInstitute of Sports Medicine Copenhagen, Department of Orthopedic Surgery M, Bispebjerg Hospital, Nielsine Nielsenvej 11, 2400, Copenhagen NV, Denmark.
University of Copenhagen · DKDuke University · USVanderbilt University · US

Funding

Lundbeckfonden R198-2015-207Nordea-fonden Healthy Aging grantNovo Nordisk Fonden NNF16OC0022846
6 · The paper itself

Abstract

Integrins are important for mechanosensation in tissue and play, together with nutrition, a role in regulating extracellular matrix (ECM) in skeletal muscle and tendon. Integrin receptors are dimers that consist of an α and β subunit and bridge extracellular and intracellular signals. The present study investigates whether the deletion of the integrin receptor α

Indexed as

Extracellular MatrixAchilles TendonAnimalsCollagenDiet, High-FatIntegrin alpha1MaleMiceMice, Inbred C57BLMice, KnockoutMuscle, SkeletalObesityCollagenIntegrin alpha1IntegrinMuscleTendon

Identifiers

PMID32112256
OpenAlexW3008999567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.