Evidence map›Paper›PMID 32112134›Full record

ReviewApplied microbiology and biotechnology2020

Application of vitamin-producing lactic acid bacteria to treat intestinal inflammatory diseases.

Jean Guy LeBlanc, Romina Levit, Graciela Savoy de Giori, Alejandra de Moreno de LeBlanc

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Impact of lactic acid bacteria andVeterinary and animal science · 2026
    Article
  3. Review
  4. Article
  5. Lactobacilli and gut pH: features of correlation in model experiments.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Assessment of various standard fish diets on gut microbiome of platyfish Xiphophorus maculatus.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024
    Article
  13. The Plethora of Microbes with Anti-Inflammatory Activities.International journal of molecular sciences · 2024
    Review
  14. Article
  15. Exopolysaccharide fromFrontiers in nutrition · 2024
    Article
  16. Effect ofFrontiers in microbiology · 2024
    Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jean Guy LeBlanc *Centro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, T4000ILC, San Miguel de Tucumán, Tucumán, Argentina. leblanc@cerela.org.ar.ORCID http://orcid.org/0000-0002-4634-8630
Romina LevitCentro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, T4000ILC, San Miguel de Tucumán, Tucumán, Argentina.
Graciela Savoy de GioriCentro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, T4000ILC, San Miguel de Tucumán, Tucumán, Argentina.
Alejandra de Moreno de LeBlanc *Centro de Referencia para Lactobacilos (CERELA-CONICET), Chacabuco 145, T4000ILC, San Miguel de Tucumán, Tucumán, Argentina. demoreno@cerela.org.ar.
Centro Científico Tecnológico - Tucumán · ARNational University of Tucumán · AR

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas projects PIP 0697CYTED Ciencia y Tecnología para el Desarrollo 917PTE0537Fondo para la Investigación Científica y Tecnológica PICT 2016-0301
6 · The paper itself

Abstract

Recent studies have shown that inflammatory diseases are becoming more frequent throughout the world. The causes of these disorders are multifactorial and include genetic, immunological, and environmental factors, and intestinal microbiota dysbiosis. The use of beneficial microorganisms has shown to be useful in the prevention and treatment of disorders such as colitis, mucositis, and even colon cancer by their immune-stimulating properties. It has also been shown that certain vitamins, especially riboflavin and folate derivatives, have proven to be helpful in the treatment of these diseases. The application of vitamin-producing lactic acid bacteria, especially strains that produce folate and riboflavin together with immune-stimulating strains, could be used as adjunct treatments in patients suffering from a wide range of inflammatory diseases since they could improve treatment efficiency and prevent undesirable side effects in addition to their nutrition values. In this review, the most up to date information on the current knowledge and uses of vitamin-producing lactic acid bacteria is discussed in order to stimulate further studies in this field.

Indexed as

AnimalsAnti-Inflammatory AgentsClinical Trials as TopicColitisFolic AcidHumansInflammationInflammatory Bowel DiseasesLactobacillalesProbioticsRiboflavinVitamin KVitaminsAnti-Inflammatory AgentsFolic AcidRiboflavinVitamin KVitaminsColitisFolateInflammationLactic acid bacteriaMucositisRiboflavin

Identifiers

PMID32112134
OpenAlexW3007789311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.