Evidence map›Paper›PMID 32112054›Full record

ReviewNature reviews. Clinical oncology2020

Tissue-resident memory T cells in breast cancer control and immunotherapy responses.

Ann Byrne, Peter Savas, Sneha Sant, Ran Li, Balaji Virassamy, Stephen J Luen, Paul A Beavis, Laura K Mackay, Paul J Neeson, Sherene Loi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

192 citing papers in PubMed, 1 synthesis or guideline pooled it, 318 citations in OpenAlex.

  1. Pooled it
  2. CD8MedComm · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Cancer Stem Cells Shift Metabolite Acetyl-Coenzyme A to Abrogate the Differentiation of CD103Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Article
  12. Tissue-resident memory T cells reshapeFrontiers in immunology · 2026
    Review
  13. Review
  14. 25HC regulates the polarization of CD163Frontiers in immunology · 2026
    Article
  15. Tumor-embedded Immunity and TRM Cell Functions in Cancer.Mini reviews in medicinal chemistry · 2026
    Review
  16. Functional, Pharmacogenomic, and Immune Landscapes of Long Non-Coding RNAs in Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Review

132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ann ByrneDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.
Peter SavasDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-5999-428X
Sneha SantDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.
Ran LiDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.
Balaji VirassamyDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-7341-8104
Stephen J LuenDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-6962-2906
Paul A BeavisDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.
Laura K MackayDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Paul J NeesonDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia.
Sherene LoiDivision of Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Victoria, Australia. sherene.loi@petermac.org.ORCID http://orcid.org/0000-0001-6137-9171
The University of Melbourne · AURoyal Women's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of tumour-infiltrating lymphocytes (TILs) is associated with favourable outcomes in patients with breast cancer as well as in those with other solid tumours. T cells make up a considerable proportion of TILs and current evidence suggests that CD8

Indexed as

Antibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalBreast NeoplasmsCD8-Positive T-LymphocytesErb-b2 Receptor Tyrosine KinasesHumansImmunologic MemoryImmunologic SurveillanceImmunotherapy, AdoptiveLymphocytes, Tumor-InfiltratingT-LymphocytesT-Lymphocyte SubsetsTriple Negative Breast NeoplasmsAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalatezolizumabERBB2 protein, humanErb-b2 Receptor Tyrosine Kinasespembrolizumab

Identifiers

PMID32112054
OpenAlexW3008954267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.