Evidence map›Paper›PMID 32111986›Full record

ArticleNature protocols2020

Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [

Florian Guibbal, Patrick G Isenegger, Thomas C Wilson, Anna Pacelli, Damien Mahaut, Jeroen B I Sap, Nicholas J Taylor, Stefan Verhoog, Sean Preshlock, Rebekka Hueting and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature protocols, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 54 citations in OpenAlex.

  1. Chemical science · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Parotidectomy Trends Toward Outpatient for Benign Disease.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  6. One-Step Synthesis of [ACS central science · 2024
    Article
  7. [Journal of clinical medicine · 2024
    Review
  8. Radiosynthesis and biological evaluation of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  9. Article
  10. Article
  11. State of the art procedures towards reactive [EJNMMI radiopharmacy and chemistry · 2023
    Review
  12. Concise and Scalable Radiosynthesis of (+)-[ACS chemical neuroscience · 2023
    Article
  13. Article
  14. Radiosynthesis and Preclinical Evaluation of anPharmaceuticals (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Exploration of alcohol-enhanced Cu-mediated radiofluorination toward practical labeling.Journal of labelled compounds & radiopharmaceuticals · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Florian Guibbal *Chemistry Research Laboratory, University of Oxford, Oxford, UK.
Patrick G Isenegger *Chemistry Research Laboratory, University of Oxford, Oxford, UK.
Thomas C Wilson *Chemistry Research Laboratory, University of Oxford, Oxford, UK.
Anna PacelliRadiobiology Research Institute, Department of Oncology, Churchill Hospital, University of Oxford, Headington, UK.
Damien MahautChemistry Research Laboratory, University of Oxford, Oxford, UK.
Jeroen B I SapChemistry Research Laboratory, University of Oxford, Oxford, UK.
Nicholas J TaylorChemistry Research Laboratory, University of Oxford, Oxford, UK.
Stefan VerhoogChemistry Research Laboratory, University of Oxford, Oxford, UK.
Sean PreshlockChemistry Research Laboratory, University of Oxford, Oxford, UK.
Rebekka HuetingRadiobiology Research Institute, Department of Oncology, Churchill Hospital, University of Oxford, Headington, UK.
Bart CornelissenRadiobiology Research Institute, Department of Oncology, Churchill Hospital, University of Oxford, Headington, UK. bart.cornelissen@oncology.ox.ac.uk.ORCID http://orcid.org/0000-0001-7581-3303
Véronique GouverneurChemistry Research Laboratory, University of Oxford, Oxford, UK. veronique.gouverneur@chem.ox.ac.uk.ORCID http://orcid.org/0000-0001-8638-5308
University of Oxford · GBChurchill Hospital · GB

Funding

Cancer Research UK 16466Cancer Research UK 23970Medical Research Council MR/R01695X/1
6 · The paper itself

Abstract

Positron emission tomography (PET) is a diagnostic nuclear imaging modality that relies on automated protocols to prepare agents labeled with a positron-emitting radionuclide (e.g.,

Indexed as

PhthalazinesPiperazinesPoly(ADP-ribose) Polymerase InhibitorsAutomationChemistry Techniques, SyntheticCopperFluorine RadioisotopesPositron-Emission TomographyRadiochemistryRadiopharmaceuticalsCopperFluorine RadioisotopesolaparibPhthalazinesPiperazinesPoly(ADP-ribose) Polymerase InhibitorsRadiopharmaceuticals

Identifiers

PMID32111986
OpenAlexW3007949777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.