Trial reportScientific reports2020
Spatio-temporal dynamics of Plasmodium falciparum transmission within a spatial unit on the Colombian Pacific Coast.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- A systematic review of sample size estimation accuracy on power in malaria cluster randomised trials measuring epidemiological outcomes.BMC medical research methodology · 2024Pooled it
- Are pfhrp2 and pfhrp3 Deletions a Concern in Latin America? A Critical Review.Pathogens (Basel, Switzerland) · 2026Review
- Antimalarial drug resistance inParasitology · 2026Article
- Anopheles mosquito fauna, blood meal sources and transmission intensity from high and moderate malaria endemic areas of Ethiopia.Scientific reports · 2025Article
- Prevalence of pfhrp2/pfhrp3 gene deletions among patients with Plasmodium falciparum malaria with false-negative in the HRP2-based rapid diagnostic test in Colombia.Memorias do Instituto Oswaldo Cruz · 2025Article
- The role of connectivity on malaria dynamics across areas with contrasting control coverage in the Peruvian Amazon.PLoS neglected tropical diseases · 2024Article
- Spatio-temporal characterization of malaria prevalence in a peri-urban resource limited setting of Western Kenya Highlands.African health sciences · 2024Article
- Genomic surveillance of malaria parasites in an indigenous community in the Peruvian Amazon.Scientific reports · 2024Article
- Gene regulatory network topology governs resistance and treatment escape in glioma stem-like cells.Science advances · 2024Article
- Evaluating the performance of Plasmodium falciparum genetic metrics for inferring National Malaria Control Programme reported incidence in Senegal.Malaria journal · 2024Article
- A Qualitative Analysis of the Perceptions of Stakeholders Involved in Vector Control and Vector-Borne Disease Research and Surveillance in Orinoquia, Colombia.Tropical medicine and infectious disease · 2024Article
- Evaluating the performance of Plasmodium falciparum genetics for inferring National Malaria Control Program reported incidence in Senegal.Research square · 2023Article
- Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis.PLoS pathogens · 2022Article
- Design and implementation of multiplexed amplicon sequencing panels to serve genomic epidemiology of infectious disease: A malaria case study.Molecular ecology resources · 2022Article
- Malaria prevalence in Commune 5 in Tumaco (Nariño, Colombia).F1000Research · 2022Article
- Malaria epidemics in Colombia, 1970-2019.Revista da Sociedade Brasileira de Medicina Tropical · 2022Article
- Evidence of a Recent Bottleneck inPathogens (Basel, Switzerland) · 2021Article
- Analysing human population movement data for malaria control and elimination.Malaria journal · 2021Review
- Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin.PLoS neglected tropical diseases · 2021Article
- Anopheles arabiensis hotspots along intermittent rivers drive malaria dynamics in semi-arid areas of Central Ethiopia.Malaria journal · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 10 institutions in 5 countries.
Funding
Abstract
As malaria control programmes concentrate their efforts towards malaria elimination a better understanding of malaria transmission patterns at fine spatial resolution units becomes necessary. Defining spatial units that consider transmission heterogeneity, human movement and migration will help to set up achievable malaria elimination milestones and guide the creation of efficient operational administrative control units. Using a combination of genetic and epidemiological data we defined a malaria transmission unit as the area contributing 95% of malaria cases diagnosed at the catchment facility located in the town of Guapi in the South Pacific Coast of Colombia. We provide data showing that P. falciparum malaria transmission is heterogeneous in time and space and analysed, using topological data analysis, the spatial connectivity, at the micro epidemiological level, between parasite populations circulating within the unit. To illustrate the necessity to evaluate the efficacy of malaria control measures within the transmission unit in order to increase the efficiency of the malaria control effort, we provide information on the size of the asymptomatic reservoir, the nature of parasite genotypes associated with drug resistance as well as the frequency of the Pfhrp2/3 deletion associated with false negatives when using Rapid Diagnostic Tests.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.