ArticleNature communications2020
Stem rust resistance in wheat is suppressed by a subunit of the mediator complex.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 60 citations in OpenAlex.
- Discovery of a novel non-race-specific adult-plant resistance (APR) locus conferring stripe rust immunity in spelt wheat and its suppression in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Mapping novel yellow and leaf rust loci and predicting resistance in cross derived Canadian durum wheat.The plant genome · 2025Article
- Harnessing primary, secondary and tertiary genepools for durable wheat disease resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Genome-wide atlas of rust resistance loci in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Genomic prediction of synthetic hexaploid wheat upon tetraploid durum and diploid Aegilops parental pools.The plant genome · 2024Article
- Genetic dissection and identification of stripe rust resistance genes in the wheat cultivar Lanhangxuan 121, a cultivar selected from a space mutation population.Molecular breeding : new strategies in plant improvement · 2024Article
- Wheat Pm55 alleles exhibit distinct interactions with an inhibitor to cause different powdery mildew resistance.Nature communications · 2024Article
- Introgression of the bread wheat D genome encoded Lr34/Yr18/Sr57/Pm38/Ltn1 adult plant resistance gene into Triticum turgidum (durum wheat).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Identification of the Solid Stem Suppressor GeneInternational journal of molecular sciences · 2023Article
- MEDIATOR SUBUNIT 16 negatively regulates rice immunity by modulating PATHOGENESIS RELATED 3 activity.Plant physiology · 2023Article
- FHB resistance conferred by Fhb1 is under inhibitory regulation of two genetic loci in wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Global transcriptome analysis of allopolyploidization reveals large-scale repression of the D-subgenome in synthetic hexaploid wheat.Communications biology · 2023Article
- Identification of a suppressor for the wheat stripe rust resistance gene Yr81 in Chinese wheat landrace Dahongpao.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Mapping a leaf rust resistance geneFrontiers in plant science · 2023Article
- Plant and pathogen genomics: essential approaches for stem rust resistance gene stacks in wheat.Frontiers in plant science · 2023Review
- Article
- Discovery of stripe rust resistance with incomplete dominance in wild emmer wheat using bulked segregant analysis sequencing.Communications biology · 2022Article
- Capturing Wheat Phenotypes at the Genome Level.Frontiers in plant science · 2022Review
- Characterization of synthetic wheat line Largo for resistance to stem rust.G3 (Bethesda, Md.) · 2021Article
- The Arabidopsis mediator complex subunit 8 regulates oxidative stress responses.The Plant cell · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 10 institutions in 6 countries.
Funding
Abstract
Stem rust is an important disease of wheat that can be controlled using resistance genes. The gene SuSr-D1 identified in cultivar 'Canthatch' suppresses stem rust resistance. SuSr-D1 mutants are resistant to several races of stem rust that are virulent on wild-type plants. Here we identify SuSr-D1 by sequencing flow-sorted chromosomes, mutagenesis, and map-based cloning. The gene encodes Med15, a subunit of the Mediator Complex, a conserved protein complex in eukaryotes that regulates expression of protein-coding genes. Nonsense mutations in Med15b.D result in expression of stem rust resistance. Time-course RNAseq analysis show a significant reduction or complete loss of differential gene expression at 24 h post inoculation in med15b.D mutants, suggesting that transcriptional reprogramming at this time point is not required for immunity to stem rust. Suppression is a common phenomenon and this study provides novel insight into suppression of rust resistance in wheat.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.