Trial reportIn vivo (Athens, Greece)
Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study: A Five-year Follow-up.
Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Patient preferences for breast cancer screening: a systematic review update to inform recommendations by the Canadian Task Force on Preventive Health Care.Systematic reviews · 2024Pooled it
- Network analysis of quality of life and depression in a randomized breast cancer trial with ten-years follow-up.Scientific reports · 2026Trial
- Kinect-Based Mixed Reality Exercise Program Improves Physical Function and Quality of Life in Breast Cancer Survivors: A Randomized Clinical Trial.Cancer research and treatment · 2025Trial
- The Impact of Physical Activity Levels on Sexual Function in Breast Cancer Survivors: An Integrative Review.Journal of the advanced practitioner in oncology · 2026Review
- Assessment of sexual function in postmenopausal breast cancer survivors.Sexual medicine · 2024Article
- Does participation in therapeutic exercise programs after finishing oncology treatment still ensure an adequate health status for long-term breast cancer survivors? A ≥ 5 years follow-up study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Observational
- Article
- Sexual Health after a Breast Cancer Diagnosis: Addressing a Forgotten Aspect of Survivorship.Journal of clinical medicine · 2022Review
- Utility values and its time to deterioration in breast cancer patients after diagnosis and during treatments.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Interventions to Improve Sexual Health in Women Living with and Surviving Cancer: Review and Recommendations.Cancers · 2021Review
- French-language adaptation of the 16D and 17D Quality of Life measures and score description in two Canadian pediatric samples.Health psychology and behavioral medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimAs the number of breast cancer survivors is increasing, their long-term health-related quality of life (HRQoL) has become an important issue. The aim of the study is to follow up the HRQoL of breast cancer survivors (BCS) in a prospective randomized exercise intervention study and to compare HRQoL to that of the age-matched general female population. PATIENTS AND
methodsFollowing adjuvant treatment, 537 patients aged 35-68 and capable of exercise training were randomized to a 12-month exercise trial. In 182 of those patients, HRQoL was measured by the generic 15D at baseline and followed up for five years. Furthermore, the HRQoL of all BCS answering the 15D at five-year follow-up (n=390) was compared to that of a representative sample of the general population.
resultsAfter five years, the BCS' mean HRQoL demonstrated a statistically and clinically significant impairment compared to that of the general population (difference -0.023, p<0.001). The mean HRQoL of BCS followed up from baseline until five years did not improve significantly (change=0.007, p=0.27), whereas the dimensions of usual activities (0.043, p=0.004), depression (0.038, p=0.007), distress (0.030, p=0.036), and sexual activity (0.057, p=0.009) did.
conclusionThe HRQoL of BCS was still impaired five years following treatment.
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