Evidence map›Paper›PMID 32111715›Full record

Observational studyBMJ open diabetes research & care2020

Clinical characteristics and outcomes of patients with end-stage renal disease hospitalized with diabetes ketoacidosis.

Rodolfo J Galindo, Francisco J Pasquel, Maya Fayfman, Katerina Tsegka, Neil Dhruv, Saumeth Cardona, Heqiong Wang, Priyathama Vellanki, Guillermo E Umpierrez

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Diabetes and Glucose Management in People on Hemodialysis.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Article
  17. Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rodolfo J GalindoDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-9295-3225
Francisco J PasquelDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.
Maya FayfmanDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.
Katerina TsegkaDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.
Neil DhruvDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.
Saumeth CardonaDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.
Heqiong WangRollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Priyathama VellankiDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-6544-015X
Guillermo E UmpierrezDivision of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA geumpie@emory.edu.ORCID 0000-0002-3252-5026
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Emory University BIRCWH ProgramK12HD085850 · NICHD · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, STERK, CLAIRE E · 2015 to 2023
$4.4M
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery PatientsK23GM128221 · NIGMS · EMORY UNIVERSITY · PI PASQUEL, FRANCISCO J · 2018 to 2022
$957k
Use of Continuous Glucose Monitoring (CGM) in End-Stage Renal Disease(ESRD) Patients with Type 2 DiabetesK23DK123384 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALINDO, RODOLFO · 2020 to 2024
$934k
Epigenetic Markers of Short- and Long- Term Near-Normoglycemia Remission in Patients with Ketosis-Prone DiabetesK23DK113241 · NIDDK · EMORY UNIVERSITY · PI VELLANKI, PRIYATHAMA · 2019 to 2021
$646k
NCATS NIH HHS UL1 TR002378NICHD NIH HHS K12 HD085850NIDDK NIH HHS K23 DK113241NIDDK NIH HHS K23 DK123384NIGMS NIH HHS K23 GM128221
6 · The paper itself

Abstract

introductionThere is limited evidence to guide management in patients with end-stage renal disease (ESRD) on chronic hemodialysis admitted with diabetes ketoacidosis. Thus, we investigated the clinical characteristics and outcomes of patients with ESRD admitted with diabetic ketoacidosis (DKA).

methodsIn this observational study, we used International Classification of Diseases Ninth/Tenth Revision codes to identify adult (aged 18-80 years) patients admitted to Emory University Hospitals between 1 January 2006 and 31 December 2016. DKA and ESRD diagnoses were confirmed by reviewing medical records and by admission laboratory results.

resultsAmong 307 patients with DKA meeting the inclusion and exclusion criteria, 22.1% (n: 68) had ESRD on hemodialysis and 77.9% (n: 239) had preserved renal function (estimated glomerular filtration rate >60 mL/min/1.73 m

conclusionsPatients with DKA and ESRD on chronic hemodialysis had worse clinical outcomes including higher rates of hypoglycemia, volume overload, need for mechanical ventilation and longer length of stay, compared with patients with preserved kidney function.

Indexed as

Hospital MortalityLength of StayRenal DialysisAdolescentAdultAgedAged, 80 and overBlood GlucoseDiabetic KetoacidosisFemaleGlycated HemoglobinHospitals, UniversityHumansHypoglycemiaKidney Failure, ChronicMaleBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humandialysisESRDhypoglycemiaketoacidosis

Identifiers

PMID32111715
PMCPMC7050364
OpenAlexW3007382256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.