Evidence map›Paper›PMID 32111688›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Development and Evaluation of Interleukin-2-Derived Radiotracers for PET Imaging of T Cells in Mice.

Elly L van der Veen, Frans V Suurs, Frederik Cleeren, Guy Bormans, Philip H Elsinga, Geke A P Hospers, Marjolijn N Lub-de Hooge, Elisabeth G E de Vries, Erik F J de Vries, Inês F Antunes

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. ICOS-Targeted Peptide Imaging Informs Therapeutic Response of STING Agonist in Lung Adenocarcinoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  3. Challenges in tracer development for tumor microenvironment (TME) imaging.European journal of nuclear medicine and molecular imaging · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Immune checkpoint inhibition: a future guided by radiology.The British journal of radiology · 2023
    Review
  15. Article
  16. Review
  17. Imaging of Activated T Cells.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Review
  18. Review
  19. Review
  20. Glucose-Thymidine Ratio as a Metabolism Index UsingInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Elly L van der VeenDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Frans V SuursDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Frederik CleerenLaboratory for Radiopharmaceutical Research, Department of Pharmacy and Pharmacology, University of Leuven, Leuven, Belgium.
Guy BormansLaboratory for Radiopharmaceutical Research, Department of Pharmacy and Pharmacology, University of Leuven, Leuven, Belgium.
Philip H ElsingaDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; and.
Geke A P HospersDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marjolijn N Lub-de HoogeDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; and.
Elisabeth G E de VriesDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Erik F J de VriesDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; and.
Inês F AntunesDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; and i.farinha.antunes@umcg.nl.
University Medical Center Groningen · NLKU Leuven · BEUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently,

Indexed as

AnimalsBALB 3T3 CellsDrug DiscoveryFluorine RadioisotopesGallium RadioisotopesHumansInterleukin-2MicePositron-Emission TomographyRadioactive TracersTissue DistributionT-LymphocytesFluorine-18Fluorine RadioisotopesGallium-68Gallium RadioisotopesInterleukin-2Radioactive Tracersimmunotherapyinterleukin-2PET imagingradiopharmaceuticalsT cells

Identifiers

PMID32111688
PMCPMC7456170
OpenAlexW3007302772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.