Evidence map›Paper›PMID 32111652›Full record

ArticleG3 (Bethesda, Md.)2020

RhoBTB Proteins Regulate the Hippo Pathway by Antagonizing Ubiquitination of LKB1.

Thanh Hung Nguyen, Adela Ralbovska, Jan-Michael Kugler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thanh Hung NguyenDepartment of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Adela RalbovskaDepartment of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Jan-Michael KuglerDepartment of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark jmkugler@sund.ku.dk.ORCID 0000-0001-6791-2694
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Hippo pathway regulates growth and apoptosis. We identify RhoBTB proteins as novel regulators of Hippo signaling. RhoBTB depletion in the

Indexed as

Drosophila ProteinsProtein Serine-Threonine KinasesSignal TransductionAMP-Activated Protein Kinase KinasesAnimalsDrosophila melanogasterGTP-Binding ProteinsHippo Signaling PathwayHumansIntracellular Signaling Peptides and ProteinsNuclear ProteinsProtein KinasesTrans-ActivatorsUbiquitinationAMP-Activated Protein Kinase KinasesDrosophila ProteinsGTP-Binding ProteinsIntracellular Signaling Peptides and ProteinsLKB1 protein, DrosophilaNuclear ProteinsProtein KinasesProtein Serine-Threonine KinasesRhoBTB protein, DrosophilaTrans-ActivatorsHippo pathwayLKB1 (STK11)RhoBTBubiquitination

Identifiers

PMID32111652
PMCPMC7144079
OpenAlexW3006910133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.