Evidence map›Paper›PMID 32111560›Full record

ReviewPediatric neurology2020

Cerebrovascular Complications of Pediatric Blunt Trauma.

Maria M Galardi, Jennifer M Strahle, Alex Skidmore, Akash P Kansagra, Kristin P Guilliams

Abstract readReview
In one paragraph

Review in Pediatric neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria M GalardiDepartment of Neurology, Washington University School of Medicine, St. Louis, Missouri.
Jennifer M StrahleDepartment of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri.
Alex SkidmoreDepartment of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri.
Akash P KansagraDepartment of Neurology, Washington University School of Medicine, St. Louis, Missouri; Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Kristin P GuilliamsDepartment of Neurology, Washington University School of Medicine, St. Louis, Missouri; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri. Electronic address: kristinguilliams@wustl.edu.

Funding

Age-Dependence of Cerebral Oxygen Metabolism and Stroke Risk in Pediatric Sickle Cell DiseaseK23NS099472 · NINDS · WASHINGTON UNIVERSITY · PI GUILLIAMS, KRISTIN · 2017 to 2021
$951k
NINDS NIH HHS K23 NS099472NINDS NIH HHS L40 NS108300
6 · The paper itself

Abstract

Ischemic and hemorrhagic stroke can occur in the setting of pediatric trauma, particularly those with head or neck injuries. The risk of stroke appears highest within the first two weeks after trauma. Stroke diagnosis may be challenging due to lack of awareness or concurrent injuries limiting detailed neurological assessment. Other injuries may also complicate stroke management, with competing priorities for blood pressure, ventilator management, or antithrombotic timing. Here we review epidemiology, clinical presentation, and diagnostic approach to blunt arterial injuries including dissection, cerebral sinovenous thrombosis, mineralizing angiopathy, stroke from abusive head trauma, and traumatic hemorrhagic stroke. Owing to the complexities and heterogeneity of concomitant injuries in stroke related to trauma, a single pathway for stroke management is impractical. Therefore providers must understand the goals and possible costs or consequences of stroke management decisions to individualize patient care. We discuss the physiological principles of cerebral perfusion and oxygen delivery, considerations for ventilator strategy when stroke and lung injury are present, and current available evidence of the risks and benefits of anticoagulation to provide a framework for multidisciplinary discussions of cerebrovascular injury management in pediatric patients with trauma.

Indexed as

Intracranial Arterial DiseasesIntracranial HemorrhagesIntracranial ThrombosisStrokeChildCraniocerebral TraumaHumansWounds, NonpenetratingArterial dissectionCerebrovascular traumaChildCraniocerebral traumaHemorrhageHumansStrokeThrombosis

Identifiers

PMID32111560
PMCPMC7306436

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.