Evidence map›Paper›PMID 32111379›Full record

ArticleThe Journal of pediatrics2020

Antibiotic Prescribing Patterns for Acute Otitis Media for Children 2 Years and Older.

Holly M Frost, Lauren F Becker, Bryan C Knepper, Katherine C Shihadeh, Timothy C Jenkins

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  8. Cost to implement an outpatient stewardship intervention for acute otitis media (AOM).Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
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  19. Next Steps in Ambulatory Stewardship.Infectious disease clinics of North America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Holly M FrostDepartment of Pediatrics, Denver Health Medical Center, Denver, CO; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO. Electronic address: Holly.Frost@dhha.org.
Lauren F BeckerDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Bryan C KnepperDepartment of Patient Safety and Quality, Denver Health Medical Center, Denver, CO.
Katherine C ShihadehDepartment of Pharmacy, Denver Health Medical Center, Denver, CO.
Timothy C JenkinsDivision of Infectious Diseases and Department of Medicine, Denver Health Medical Center, Denver, CO; Department of Internal Medicine-Infectious Diseases, University of Colorado School of Medicine, Aurora, CO.

Funding

Rapid diagnostic tests for adenovirus conjunctivitis in children: An epidemiologic, clinical, and cost-effectiveness evaluationK23HD099925 · NICHD · DENVER HEALTH AND HOSPITAL AUTHORITY · PI FROST, HOLLY · 2019 to 2023
$762k
NICHD NIH HHS K23 HD099925
6 · The paper itself

Abstract

objectiveTo determine the frequency that non-first-line antibiotics, safety-net antibiotic prescriptions (SNAPS), and longer than recommended durations of antibiotics were prescribed for children ≥2 years of age with acute otitis media and examine patient and system level factors that contributed to these outcomes. STUDY

designChildren age ≥2 years with acute otitis media seen at Denver Health Medical Center outpatient locations from January to December 2018 were included. The percentages of patients who received first-line antibiotics, SNAPs, and recommended durations of antibiotics were determined. Factors associated with non-first-line and longer than recommended antibiotic durations were evaluated using multivariate logistic regression modeling.

resultsOf the 1025 visits evaluated, 98.0% were prescribed an antibiotic; only 4.5% of antibiotics were SNAPs. Non-first-line antibiotics were prescribed to 18.8% of patients. Most antibiotic durations (94.1%) were longer than the institution recommended 5 days and 54.3% were ≥10 days. Private insurance was associated with non-first-line antibiotics (aOR, 1.89; 95% CI, 1; 14-3.14, P = .01). Patients who were younger (2-5 years; aOR 2.01; 95% CI, 1.32-3.05; P < .001) or seen in emergency/urgent care sites (aOR, 1.73; 95% CI, 1.26-2.38; P < .001) were more likely to receive ≥10 days of antibiotic compared with those in pediatric clinics.

conclusionsAntibiotic stewardship interventions that emphasize the duration of antibiotic therapy as well as the use of SNAPs or observation may be higher yield than those focusing on first-line therapy alone. Numerous system and patient level factors are associated with off-guideline prescribing.

Indexed as

Age FactorsAmbulatory Care FacilitiesAnti-Bacterial AgentsAntimicrobial StewardshipChildChild, PreschoolColoradoDrug Administration ScheduleDrug PrescriptionsEmergency Service, HospitalFemaleHumansInsurance, HealthMaleOtitis MediaPractice Patterns, Physicians'Anti-Bacterial Agentsacute otitis mediaantimicrobial stewardshipchildrendurationtreatment

Identifiers

PMID32111379
PMCPMC7249267

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.