Evidence map›Paper›PMID 32111265›Full record

ReviewOncology research2020

Sulforaphane: Expected to Become a Novel Antitumor Compound.

Geting Wu, Yuanliang Yan, Yangying Zhou, Yumei Duan, Shuangshuang Zeng, Xiang Wang, Wei Lin, Chunlin Ou, Jianhua Zhou, Zhijie Xu

Open access · hybridAbstract readReview
In one paragraph

Review in Oncology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Flavonoids extract fromWorld journal of experimental medicine · 2025
    Review
  3. Transcriptional activation ofFrontiers in plant science · 2025
    Article
  4. Sulforaphane and ophthalmic diseases.Food science & nutrition · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Efficient thermal treatment of radish (Journal of food science and technology · 2023
    Article
  12. Review
  13. Article
  14. Enhancing Bioactive Saponin Content ofMolecules (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Network Pharmacology Integrated with Transcriptomics Deciphered the Potential Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Mustard Seed (Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Geting WuDepartment of Pathology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Yuanliang YanDepartment of Pharmacy, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Yangying ZhouDepartment of Oncology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Yumei DuanDepartment of Pathology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Shuangshuang ZengDepartment of Pharmacy, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Xiang WangDepartment of Pharmacy, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Wei LinDepartment of Pathology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Chunlin OuDepartment of Pathology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Jianhua ZhouDepartment of Pathology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Zhijie XuDepartment of Pathology, Xiangya Hospital, Central South UniversityChangshaP.R. China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products are becoming increasingly popular in a variety of traditional, complementary, and alternative systems due to their potency and slight side effects. Natural compounds have been shown to be effective against many human diseases, especially cancers. Sulforaphane (SFE) is a traditional Chinese herbal medicine. In recent years, an increasing number of studies have been conducted to evaluate the antitumor effect of SFE. The roles of SFE in cancers are mainly through the regulation of potential biomarkers to activate or inhibit related signaling pathways. SFE has exhibited promising inhibitory effects on breast cancer, lung cancer, liver cancer, and other malignant tumors. In this review, we summarized the reports on the activity and functional mechanisms of SFE in cancer treatment and explored the efficacy and toxicity of SFE.

Indexed as

Antineoplastic Agents, PhytogenicApoptosisCell Line, TumorCell ProliferationFemaleHumansIsothiocyanatesMedicine, Chinese TraditionalNeoplasmsPlant ExtractsRaphanusSignal TransductionSulfoxidesAntineoplastic Agents, PhytogenicIsothiocyanatesPlant ExtractssulforaphaneSulfoxides

Identifiers

PMID32111265
PMCPMC7851526
OpenAlexW3008432654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.