Evidence map›Paper›PMID 32111095›Full record

ArticleInternational journal of molecular sciences2020

Acid Ceramidase Depletion Impairs Neuronal Survival and Induces Morphological Defects in Neurites Associated with Altered Gene Transcription and Sphingolipid Content.

Kalia Kyriakou, Carsten W Lederer, Marina Kleanthous, Anthi Drousiotou, Anna Malekkou

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kalia KyriakouCyprus School of Molecular Medicine, P.O. Box 23462, 1683 Nicosia, Cyprus.
Carsten W LedererCyprus School of Molecular Medicine, P.O. Box 23462, 1683 Nicosia, Cyprus.ORCID 0000-0003-3920-9584
Marina KleanthousCyprus School of Molecular Medicine, P.O. Box 23462, 1683 Nicosia, Cyprus.
Anthi DrousiotouCyprus School of Molecular Medicine, P.O. Box 23462, 1683 Nicosia, Cyprus.
Anna MalekkouCyprus School of Molecular Medicine, P.O. Box 23462, 1683 Nicosia, Cyprus.
Cyprus Institute of Neurology and Genetics · CY

Funding

Cyprus Institute of Neurology and Genetics Telethon grant 33173135
6 · The paper itself

Abstract

The

Indexed as

Transcription, GeneticAcid CeramidaseApoptosisCell Cycle CheckpointsCell Line, TumorCell SurvivalCeramidesDistal MyopathiesFarber LipogranulomatosisGene Knockdown TechniquesHomeostasisHumansLysosomal-Associated Membrane Protein 1Lysosomal Membrane ProteinsLysosomal Storage DiseasesLysosomesAcid CeramidaseASAH1 protein, humanCeramidesLAMP1 protein, humanLysosomal-Associated Membrane Protein 1Lysosomal Membrane Proteinsrho GTP-Binding ProteinsRNA, MessengerSphingolipidsacid ceramidaseceramideLAMP1lipidomicsneuritesRho GTPasesSH-SY5Y

Identifiers

PMID32111095
PMCPMC7084529
OpenAlexW3006729404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.