Evidence map›Paper›PMID 32110997›Full record

ArticleGenes2020

Identification of the Differentially Expressed Genes of Muscle Growth and Intramuscular Fat Metabolism in the Development Stage of Yellow Broilers.

Dongfeng Li, Zaixu Pan, Kun Zhang, Minli Yu, Debing Yu, Yinglin Lu, Jiantao Wang, Jin Zhang, Kangning Zhang, Wenxing Du

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dongfeng LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Zaixu PanCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Kun ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Minli YuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Debing YuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yinglin LuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jiantao WangAnimal Husbandry Station, Agriculture and Animal Husbandry Bureau of Tangshan Ctiy, Tangshan 063000, China.
Jin ZhangJiangsu Lihua Animal Husbandry Co., Ltd. Changzhou 213168, China.
Kangning ZhangJiangsu Lihua Animal Husbandry Co., Ltd. Changzhou 213168, China.
Wenxing DuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CNJiangsu Agri-animal Husbandry Vocational College · CNShandong Province Animal Husbandry and Veterinary Bureau · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-quality chicken meat is an important source of animal protein for humans. Gene expression profiles in breast muscle tissue were determined, aiming to explore the common regulatory genes relevant to muscle and intramuscular fat (IMF) during the developmental stage in chickens. Results show that breast muscle weight (BMW), breast meat percentage (BMP, %), and IMF (%) continuously increased with development. A total of 256 common differentially expressed genes (DEGs) during the developmental stage were screened. Among them, some genes related to muscle fiber hypertrophy were upregulated (e.g., CSRP3, LMOD2, MUSTN1, MYBPC1), but others (e.g., ACTC1, MYL1, MYL4) were downregulated from Week 3 to Week 18. During this period, expression of some DEGs related to the cells cycle (e.g., CCNB3, CCNE2, CDC20, MCM2) changed in a way that genetically suggests possible inhibitory regulation on cells number. In addition, DEGs associated with energy metabolism (e.g., ACOT9, CETP, LPIN1, DGAT2, RBP7, FBP1, PHKA1) were found to regulate IMF deposition. Our data identified and provide new insights into the common regulatory genes related to muscle growth, cell proliferation, and energy metabolism at the developmental stage in chickens.

Indexed as

MeatAdipose TissueAnimalsChickensGene Expression Regulation, DevelopmentalLipid MetabolismMuscle ProteinsMuscle, SkeletalMuscle Proteinschickenfat metabolismgene expression profilingmolecular regulationmuscle development

Identifiers

PMID32110997
PMCPMC7140879
OpenAlexW3008023116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.