Evidence map›Paper›PMID 32110987›Full record

ArticleCells2020

Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis.

Jizheng Guo, Jie Li, Lin Xia, Yang Wang, Jinhang Zhu, Juan Du, Yungang Lu, Guodong Liu, Xiaoqiang Yao, Bing Shen

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. METTL7A-Dependent mMedComm · 2026
    Article
  2. Article
  3. Article
  4. Phospholipid scramblase 1: a frontline defense against viral infections.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Article
  6. TRP Channels in Stroke.Neuroscience bulletin · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Mechanisms and significance of CaCurrent opinion in physiology · 2020
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Jizheng GuoSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Jie LiSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Lin XiaSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Yang WangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Jinhang ZhuSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Juan DuSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Yungang LuBrown Foundation Institute of Molecular Medicine, University of Texas, McGovern Medical School, Houston, TX 77030, USA.
Guodong LiuInstitute of Biomedical and Health, School of Life and Health Science, Anhui Science & Technology University, Fengyang, Anhui 233100, China.
Xiaoqiang YaoSchool of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China.
Bing ShenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Anhui Medical University · CNAnhui Science and Technology University · CNBrown Foundation · USChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phospholipid scramblase 1 (PLSCR1), a lipid-binding and Ca

Indexed as

ApoptosisExocytosisAnimalsCell MembraneHEK293 CellsHumansIon Channel GatingMice, KnockoutNeuronsPhosphatidylserinesPhospholipid Transfer ProteinsProtein BindingReperfusion InjurySignal TransductionTRPC Cation ChannelsPhosphatidylserinesPhospholipid Transfer ProteinsPLSCR1 protein, humanPlscr1 protein, mouseTRPC5 protein, humanTrpc5 protein, mouseTRPC Cation Channelsapoptosiscerebral ischemia reperfusionphosphatidylserinePLSCR1scramblaseTRPC5

Identifiers

PMID32110987
PMCPMC7140530
OpenAlexW3007318136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.