Evidence map›Paper›PMID 32110986›Full record

Trial reportNutrients2020

Supplementation with a Mango Leaf Extract (Zynamite®) in Combination with Quercetin Attenuates Muscle Damage and Pain and Accelerates Recovery after Strenuous Damaging Exercise.

Marcos Martin-Rincon, Miriam Gelabert-Rebato, Victor Galvan-Alvarez, Angel Gallego-Selles, Miriam Martinez-Canton, Laura Lopez-Rios, Julia C Wiebe, Saul Martin-Rodriguez, Rafael Arteaga-Ortiz, Cecilia Dorado and 4 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Acute Supplementation of Soluble Mango Leaf Extract (ZynamitePharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Life (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Review
  14. Quercetin in Sports and Exercise: A review.International journal of exercise science · 2023
    Review
  15. Review
  16. Review
  17. Impact of Nutrition-Based Interventions on Athletic Performance during Menstrual Cycle Phases: A Review.International journal of environmental research and public health · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Marcos Martin-RinconDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Miriam Gelabert-RebatoDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Victor Galvan-AlvarezDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Angel Gallego-SellesDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Miriam Martinez-CantonDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Laura Lopez-RiosNektium Pharma, Agüimes, 35118 Las Palmas de Gran Canaria, Spain.
Julia C WiebeNektium Pharma, Agüimes, 35118 Las Palmas de Gran Canaria, Spain.
Saul Martin-RodriguezDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Rafael Arteaga-OrtizDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Cecilia DoradoDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Sergio Perez-RegaladoDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Alfredo SantanaDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
David Morales-AlamoDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Jose A L CalbetDepartment of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas de Gran Canaria, Spain.
Universidad de Las Palmas de Gran Canaria · ES

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España DEP2015-71171-RMinisterio de Economía, Industria y Competitividad, Gobierno de España DEP2017-86409-C2-1-P
6 · The paper itself

Abstract

Prolonged or unusual exercise may cause exercise-induced muscle damage (EIMD). To test whether Zynamite®, a mango leaf extract rich in the natural polyphenol mangiferin, administered in combination with quercetin facilitates recovery after EIMD, 24 women and 33 men were randomly assigned to two treatment groups matched by sex and 5 km running performance, and ran a 10 km race followed by 100 drop jumps to elicit EIMD. One hour before the competition, and every 8 hours thereafter for 24 hours, they ingested placebo (728 mg of maltodextrin) or 140 mg of Zynamite® combined with 140 mg of quercetin (double-blind). Although competition times were similar, polyphenol supplementation attenuated the muscle pain felt after the competition (6.8 ± 1.5 and 5.7 ± 2.2 a.u.,

Indexed as

ExerciseBiomarkersBody CompositionDrug Therapy, CombinationFemaleHumansLactic AcidLegLocomotionMaleMangiferaMuscle, SkeletalMyalgiaOxygen ConsumptionPhysical ExertionPlant ExtractsBiomarkersLactic AcidPlant ExtractsQuercetinantioxidant supplementationDOMSeccentric exerciseEIMDergogenic aidshuman subjectsinflammationmuscle functionpolyphenolssports nutrition

Identifiers

PMID32110986
PMCPMC7146389
OpenAlexW3008204241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.